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不同脂肪酸组分饮食对OLETF雄性大鼠胰岛素抵抗的影响 被引量：2

Effect of diet with various fatty acid composition on insulin resistance in male OLETF rats
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摘要 本研究观察不同脂肪酸组分的饮食对雄性OLETF大鼠胰岛素抵抗的影响。结果显示,进食富含ω-3多不饱和脂肪酸饮食有助于改善大鼠的胰岛素敏感性。 The effect of diet with various fatty acid composition on insulin resistance in male OLETF rats was observed. The results showed that it was beneficial to insulin sensitivity in rats fed with ω-3 polyunsaturated fatty acid-rich food.
作者 史虹莉 陆肇曾 方京冲 祝禾辰 朱禧星
机构地区 复旦大学附属华山医院糖尿病研究室
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2005年第6期565-566,共2页 Chinese Journal of Endocrinology and Metabolism
基金 上海市科学技术委员会科研项目(02DJ14052-Ⅱ)
关键词 大鼠 近交OLETF 饮食 胰岛素抵抗 肌 骨骼 脂肪酸 Rats, inbred OLETF Diet Insulin resistance Muscle, skeletal Fatty acids
分类号 R587.1 [医药卫生—内分泌]
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参考文献8

  • 1姜文宇,方京冲,史虹莉,朱禧星.气相色谱法测定血清脂肪酸组分[J].复旦学报（医学版）,2003,30(4):376-378. 被引量：7
  • 2史虹莉,方京冲,丁一蕾,刘瑜,周少玲,鹿斌,朱禧星.OLETF大鼠胰岛素抵抗及相关因素分析[J].上海医学,2003,26(3):200-203. 被引量：3
  • 3Hagvc TA. Effects of unsaturated fatty acids on cell membrane functions.Scand J Clin Lab Invest, 1988,48:381-388.
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二级参考文献13

  • 1Jump DB,Clarke SD,Thelen A,et al.Diatary polyunsaturated fatty acid regulation of gene transcription.Prog Lipid Res,1997,35(3):227
  • 2Baur LA, O' Connor J,Pan DA,et al.Relationships between the fatty acid composition of muscle and erythrocyte membrane phospholipid in young children and the effect of type of infant feeding.Lipids,2000,35(1):77
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  • 5Folch J, Lees M, Stanley GHS. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem.1957, 226:497-509.
  • 6Kawano K, Hirashima T, Mori S, et al. Establish of the OLETF rat. In: Shims K, eds. Obesity and NDDM: Lessons from the OLETF rat. Elsevier Science B. V, 1999. 1-11.
  • 7Man ZW, Kawano K, Hirashima T, et al. Obesity and NDDM:Lessons from the OLETF rat. In: Shims K, eds. Elsevier Scicence B. V, 1999. 55-65.
  • 8Kim YI, Kim CH, Choi CS, et al. Microalbuminuria is associated with the insulin resistance syndrome independent of hypertension and type 2 diabetes in the Korean population. Diabetes Res Clin Pract, 2001, 52:145-152.
  • 9Tooke J. The association between insulin resistance and endotheliopathy. Diabetes Obes Metab, 1999, 1 (Suppl 1):S17-S22.
  • 10Liu RH, Mizuta M, Kurose T, et al. Early events involved in the development of insulin resistance in Zucker fatty rat. Int J Obes Relat Metab Disord, 2002, 26:318-326.

共引文献8

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二级引证文献5

中华内分泌代谢杂志
2005年 第6期

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