摘要
目的评价经皮热消融方法治疗肝细胞性肝癌的疗效.方法 97例肝细胞性肝癌病人共190个结节接受了经皮微波或射频消融治疗.结果完全消融率93%.对直径≤2 cm、2.1～3.9 cm和≥4.0 cm的结节完全消融率分别为93%、94%和86%.局部复发率10%,直径≤2 cm、2.1～3.9 cm、≥4.0 cm的结节局部复发率分别为3%、10%和32%.1,2,3年无远处复发生存率分别为47%、35%和31%.1,2,3年累积生存率分别为76%、59%、50%.结论微波及射频热消融是治疗肝癌有效和安全的方法,但在较大肿瘤局部复发率较高.
Objective To investigate the efficacy of thermal ablation for treatment of hepatocellular carcinoma （HCC）. Methods A total of 190 nodules of HCC in 97 patients were treated with microwave or radiofrequency ablation. Results Complete ablation was achieved in 93% of the nodules. The complete ablation rates in tumors ≤2.0 cm, 2.1-3.9 cm and ≥4.0 cm in diameter were 93%, 94% and 86%, respectively. Local recurrence was found in 10% of the nodules and the recurrent rates tumors ≤2.0 cm, 2. 1-3.9 cm and ≥4.0 cm in diameter were 3%/00 , 10% and 32%, respectively. The 1-, 2- and 3-year distant recurrence-free survival rates were 47%, 35% and 31%, respectively. The 1-, 2- and 3-year cumulative survival rates were 76%, 59% and 50%, respectively. Conclusions Thermal ablation by means of microwave and radiofrequency energy application is an effective and safe therapeutic modality for HCC. Large tumors can be completely ablated but it has a significantly higher risk of local recurrence.
出处
《中华肝胆外科杂志》
CAS
CSCD
2005年第12期809-811,共3页
Chinese Journal of Hepatobiliary Surgery
关键词
癌
肝细胞
射频消融
微波消融
热消融
超声
Carcinoma, hepatocellular
Radiofrequency ablation
Microwave ablation
Thermal ablation
Ultrasound
