摘要
目的探讨嗜酸性细胞增多性皮炎和高嗜酸性细胞增多综合症的临床特征、诊断、治疗及预后,以提高对嗜酸性细胞异常增多性皮炎的认识。方法回顾性分析21例以皮肤、血液甚至骨髓嗜酸性细胞浸润为特征并伴有部分器官损害的病例。结果这些病例是具有嗜酸性细胞增多性皮炎(HED),部分病例有非典型的器官损害但不能确诊为高嗜酸性细胞增多综合症(HES)的器官浸润的一组疾病。结论这些伴有器官损害的HED可能是HES。建议对HED早期进行基因分析将有助于这些病例的治疗。
Objective To investigate the difference of hypereosinophilic dermatitis （HED） and hypereosinophilic syndrome （HES） in clinical behaviour, diagnosis, therapy and prognosis so as to help improve cognition of hypereosinophilic dermatosis. Methods Patients in our hospital from 1993-2004 which had eosinophilia in skin lesions, peripheral blood even the bone marrow with some organs lesions were reviewed. Results These patients either had characters of HED or had some organs lesions which were not surely had atypically infiltrated-organs findings of HES. Conclusion These patients which had organs lesions may be HES, Proposing gene analysis in disease of HED at early stage will be hlepful to treatment of these patients which suffer from HES.
出处
《苏州大学学报（医学版）》
CAS
北大核心
2005年第6期1088-1090,共3页
Suzhou University Journal of Medical Science
