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大叶香茶菜化学成分研究 被引量:6

Chemical constituents of Isodon macrophylla
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摘要 目的研究大叶香茶菜的化学成分。方法采用硅胶柱层析进行分离纯化化合物,根据理化性质和现代波谱技术进行结构鉴定。结果从大叶香茶菜叶的乙酸乙酯部分分离出6个二萜化合物,分别鉴定为:Epinodosin(1),Isodonoiol(2),Lasiodonin(3),Oridonin(4),AdenolinE(5),Lasiodin(6)。结论6个化合物均为已知化合物,化合物5为首次从该植物中获得。 Objective To explore the chemical constituents of lsodon macrophyllus. Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences. Results Six compounds were obtained from EtOAc extract of leaves of lsodon macrophyllus and identified as Epinodosin (1), Isodonoiol (2), Lasiodonin (3), Oridonin (4), Adenolin E (5), Lasiodin (6). Conclusion All of them are known. Compound 5 is isolated from this plant for the first time.
出处 《新乡医学院学报》 CAS 2006年第1期16-18,共3页 Journal of Xinxiang Medical University
基金 新乡医学院资助项目(编号:2004YJA26)
关键词 香茶菜属 大叶香茶菜 二萜 Rabdosia ( Bl . )Hassle. Isodon macrophyllus diterpenoids
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  • 1Wang MT, Zhao TZ, Li JC, et al. The structures of rabdosinate and rabdosinatol[J]. Acta Chemica Sinica, 1987,45:871-874.
  • 2Takeda Y,Fujita T,Chen CC. Structures of lasiocarpanin, rabdolasional, and carpalasionin: new diterpenoids from Rabdosia lasiocarpa[J]. Chem Lett, 1982: 833-836.
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  • 4Zhang RP, Zhang HJ, Lin ZW. et al. Diterpenoids from Isodon Adenoloma [J]. Phychemistry, 1992, 31 (12) : 4237-4240.
  • 5Han QB, Zhang JX, Shen YH. et al. Diterpenoids from Isodon japonicus [J]. ChineseJ Nat Med,2003, 1 (1) :16-20.

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