摘要
目的探讨靶向血管治疗脑胶质瘤的研究进展。方法分别从该方法的依据、具体方法、肿瘤血管抑制剂的开发、抗血管基因治疗、优越性以及存在问题与展望等方面对靶向血管治疗脑胶质瘤这一策略进行回顾总结。结果靶向血管治疗脑胶质瘤方法可行,前景诱人。结论随着分子生物学的发展,肿瘤血管抑制剂的不断开发和研究,对于脑胶质瘤这一血管增生极为突出的肿瘤,深入研究抗血管治疗具有重要意义。
Objective To explore the advancement of targeting antiangiogenesis therapy for glioma. Methods The therapeutic method was retrospectively summarized from several aspects as follows： foundation, detailed methods, development of inhibitor of angiogenesis of tumor, antiangiogenesis gene therapy, advantages , limitations and its prospects. Results The method on glioma is feasible and promising. Conclusion With the development of molecular biology and the exploitation of antiangiogenesis, it is of great importance for glioma which is characterized by vascular proliferation to study deeply on the antiangiogenesis therapy.
出处
《新乡医学院学报》
CAS
2006年第1期103-104,106,共3页
Journal of Xinxiang Medical University
关键词
胶质瘤
血管生成抑制
靶向血管
glioma
antiangiogenesis
targeting antiangiogenesis
