摘要
目的:建立小儿清热止咳合剂的质量标准。方法:采用薄层色谱法对小儿清热止咳合剂中的麻黄、黄芩、甘草进行定性鉴别,以高效液相色谱法对其主要药材杏仁中的苦杏仁苷进行含量测定。结果:小儿清热止咳合剂中麻黄、黄芩、甘草的供试品薄层色谱中,在与对照品色谱相应的位置上,显相同颜色的斑点;苦杏仁苷进样量在0.198μg～4.954μg范围内与峰面积积分值线性关系良好(r=1.0000)。结论:本方法简便、准确、灵敏、重现性好,可用于本品的质量控制。
OBJECTIVE： To establish the quality criteria of fevcr and cough syrup for children.METHODS： Thin layer chromatography（TLC） was employed to make qualitative determination of hcrbba ephedrae,radix scutellariae, radix glycyrrhizae in fever and cough syrup for children,and high performance liquid chromatography（HPLC） was used to determine the content of amygdaloside in its chief medicinal material,almond.RESULFS：The spots in the TLC of herbba ephedrae,radix scutellariae, radix glycyrrhizae were in the same color with those in the chromatograms of control articles.The linear range of amygdaloside was 0.198μg-4.954μg（ r = 1.0 000） . CONCLUSION ： The present method is simple, accurate sensitiveness and highly reproductive,which can be used for the quality control of this preparation.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第2期138-139,共2页
China Pharmacy
