摘要
目的探讨外周动脉粥样硬化与冠状动脉粥样硬化的关系及预测价值。方法对74例可疑冠心病患者行冠状动脉造影,其中确诊冠心病57例,正常17例。同时进行颈动脉、股动脉超声检查,对各动脉内膜中层厚度(IMT)、粥样硬化斑块及心血管危险因素同冠状动脉造影结果进行统计分析。依据修正的Gensin评分系统将冠状动脉积分,并以积分的大小进行等级评分,同时对外周动脉斑块对冠脉的预测价值、外周动脉IMT与冠脉积分的对数值进行相关性分析、冠心病组和正常组的危险因素之间进行统计分析。结果冠脉造影阳性组CA、FA的IMT和粥样硬化斑块发生率高于阴性组(P<0.05),颈动脉、股动脉粥样硬化对冠心病的阳性预测值分别为59.4%和53.1%,两处为阳性的阳性预测值是71.9%。颈动脉IMT与冠心病的log(Gensin评分)之间相关系数为0.891,股动脉IMT与冠心病的(Gensin评分)之间相关系数为0.75。结论外周动脉的粥样硬化是冠心病的相关因素,可作为研究冠状动脉粥样硬化的间接指标和窗口。
Objective To investigate the relation of peripheral atheresclerosis and coronary heart disease. Methods Atherosclerosis of carotid, femoral was investigated by ultrasound in 74 eases undergone coronary arteriography （CAG）. Correlation between extracoronary artery ultrasound results and CAG results were analyzed. The integral and grade score of coronary artery were carried out according to the modified C, ensin system. Predictive value of PDA （peripheral atherosclerosis）for coronary heart disease（CHD）, the relation between IMT and the logarithms of coronary integral score were calculated, Results CHD was verified in 57 cases and 17 cases had normal CAG. The IMT and incidence of carotid, femoral atherosclerosis plaque in patients with CHD were higher than patients with normal CAG （P〈 0,05）, The positive predictive value of carotid plaque and femoral plaque for CHD was 59.4% and 53.1% respectively. Predictive value of both carotid and femoral plaque was 71.9%. The relation coefficient of log （Gensin score） with carotid artery IMT and femoral artery IMT was 0.89 and 0.75 respectively. Conclusion The peripheral artery atheroselerosis was related with CHD.
出处
《中国心血管病研究》
CAS
2006年第2期115-118,共4页
Chinese Journal of Cardiovascular Research
