摘要
目的:探讨心肌灌注断层显像方法在病毒性心肌炎影像中半定量分析应用的诊断价值。方法:采用99Tcm-M IB I心肌灌注断层显像,分析2003-01~2005-03的108例心肌炎患者显像结果,并以36例无心肌炎患者为对照,按心肌放射性分布密集均匀程度分为3度,观察患者心肌/肝计数比值(myocard ium/liver:M/L)及心腔/心肌计数比值(chambers heart/myocard ium:C/M)在早期和/或症状较轻之心肌炎患者临床诊断中的价值。结果:虽然早期和/或症状较轻之心肌炎患者可能无花斑样改变,但心肌摄取显像剂的放射性计数通常降低,表现为M/L降低或/和C/M增高。对照组的M/L和C/M分别为1.21±0.38及0.26±0.17。108例Ⅰ、Ⅱ、Ⅲ度心肌炎患者M/L分别为1.14±0.32、1.12±0.33及1.08±0.22,与对照组比较明显降低(P<0.01和/或P<0.05);C/M分别为0.28±0.25、0.30±0.24及0.33±0.19,与对照组比较明显增高(P<0.01和/或P<0.05)。结论:M/L降低和C/M比增高,对于早期及症状较轻的病毒性心肌炎患者之诊断有一定价值。
Objective：To explore the diagnostic value of the ^99Tc^m-MIBI myocardial perfusion imaging in patients with viral myocarditis （VMC） via semiquantitative analysis pattern of the myocardial section centigram. Methods： A total of 108 patients with VMC （from Jan. 2003 to Mar. 2005） were included in this study. The control group consisted of 36 healthy individuals that received health examination only. All of the 144 subjects were examined by the ^99Tc^m-MIBI myocardial perfusion tomography. The radioactivity of ^99Tc^m-MIBI uptake on the images was graded as a score of Ⅰ to Ⅲ and the ratio of myocardium/liver （M/L） and chambers heart/myocardium （C/M） was calculated. Results：^99Tc^m-MIBI uptake on images were normal in control group, and its M/L and C/M values were 1.21 ±0.38 and 0.26 ±0.17, respectively. In 108 VMC patients, Ⅰ , Ⅱ, Ⅲ score VMC were found in 37, 39 and 32 , respectively. The M/L ratios of score Ⅰ , Ⅱ , Ⅲ groups were 1.21 ±0.38, 1.12 ±0.33 and 1.08 ± 0.22, respectively, which were significantly lower than that of control group （P 〈 0.01 or P 〈 0.05）. The C/M ratios in score Ⅰ , Ⅱ , Ⅲ subgroups were 0.28 ±0.25, 0.30 ±0.24 and 0.33 ±0.19, respectively, which were significantly higher than that of control group （ （ P 〈 0.01 or P 〈 0.05 ）. Conclusion ： The ^99Tc^m-MIBI myocardial perfusion image may be a useful diagnostic method for patients with early and mild - symptom of VMC.
出处
《西北国防医学杂志》
CAS
2006年第1期19-20,F0003,共3页
Medical Journal of National Defending Forces in Northwest China
