摘要
应用0.5%伊维菌素浇泼剂按0.3,0.4,0.5mg/kg.b w剂量对绵羊沿背中线皮肤一次浇泼给药,并以伊维菌素注射剂0.2mg/kg.b w剂量做对照。结果:伊维菌素浇泼剂0.3mg/kg,0.4mg/kg.b w剂量对消化道线虫虫卵转阴率分别为85%和90%,减少率分别为89.1%和95.9%;对原圆科线虫幼虫转阴率分别为60%和75%,减少率分别为77.2%和86.7%;0.5mg/kg.b w剂量对消化道线虫虫卵转阴率和减少率均为100%,对原圆科线虫幼虫转阴率为85%,减少率为95.4%。解剖检查结果:伊维菌素浇泼剂三种剂量对绵羊消化道、呼吸道多属线虫均有效,总计驱虫率分别为90.8%,95.6%和99.7%,伊维菌素浇泼剂0.5mg/kg.b w剂量与伊维菌素注射剂0.2mg/kg.b w剂量驱虫效果基本一致;绵羊经皮给药可耐受1.0mg/kg.b w剂量。试验证明:伊维菌素浇泼剂经皮给药驱除绵羊线虫高效安全,临床推荐剂量以0.5mg/kg.b w为宜。
The pour-sprinkling preparation of 0.5 % Ivermectin in a dose of 0.3,0.4 and 0.5mg/kg. were given to sheep by means of single pour-sprinkling the skin along center line on bodyback of sheep. Ivermectin in a dose of 0.2mg/kg. was injected as control.The results showed that negative rate of nematode ova of alimentary canal in the sheep of 0.3mg/kg. and 0.4mg/kg. groups were 85% and 90%, and the reductive rote were 89. 1% and 95.9%, respectively. The negative rate of protstrongylus larvae were 60% and 75 %, and the reductive rate were 77.2% and 86.7 %, respectively. The both negative rate and reductive rate of nematode ova of alimentary canal in the sheep of 0.5mg/kg. group were 100%, and the negative rate and reduetive rate of protstrongylus larvae in dose 0.5mg/kg. were 85% and 95.4%, respectively. The results of amatomical examination showed that the three dose of Ivermectin pour-sprikling preparation had good effect for many nematodes in alimentary canal and breath canal of sheep, The total deworming were rate 90.8%, 95.6% and 99.7%, respectively. The dewonning effect dose 0.5mg/kg. of Ivermeetin pour-sprikling preparation and 0.2mg/kg. injection was same. Shep can bear 1.0mg/kg. dose which given by skin, The experiment proved that Ivermeetin peur-sprikling preparation was effective and safe for deworming nematode by means of giving medicine through skin. The clinical recommendation dosage, was 0.5mg/kg.
出处
《青海畜牧兽医杂志》
2006年第1期7-9,共3页
Chinese Qinghai Journal of Animal and Veterinary Sciences
基金
青海省科技厅资助项目98-N-203的部分内容
关键词
伊维菌素
浇泼剂
绵羊
驱虫
安全性
Ivermectin
Pour- sprinking
Preparation
Sheep
Deworming
Safety
