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奎硫平与利培酮治疗晚发精神分裂症对照研究 被引量:4

Comparative study of quetiapine and risperidone in the treatment of late onset schizophrenias
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摘要 目的:比较奎硫平与利培酮治疗晚发精神分裂症患者的临床疗效和安全性。方法:对60例晚发精神分裂症的住院患者随机分为两组,分别用奎硫平和利培酮治疗8周。采用阳性与阴性症状量表(PANSS)评定疗效,用副反应量表(TESS)评定不良反应。结果:奎硫平与利培酮治疗晚发精神分裂症患者的临床疗效差异无显著性。两组不良反应均少而轻。结论:奎硫平治疗晚发精神分裂症疗效好,起效快,不良反应少。 Objective:To compare the efficacy and safety between quetiapinc and risperidone in the treatment of late onset schizophrenia. Method: 60 late onset schizophrenias were randomly divided into two groups. They received quetiapine and risperidone respectively for 8 weeks. The efficacies and side effects were assessed by positive and negative symptom scale (PANSS), treatment emengent symptom scale (TESS). Results:The efficacies of both quetiapine and fisperidone to treat late onset schizophrenias were similar, side effects were fewer and milder, Conclusion: Quetiapine is an effective and safe drug in the treatment of late onset schizophrcnias. Its side effects were fewer.
作者 褚建平
出处 《临床精神医学杂志》 2006年第1期34-35,共2页 Journal of Clinical Psychiatry
关键词 奎硫平 利培酮 晚发精神分裂症 quetiapine riperidone late onset schizophrenia
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