摘要
目的:比较奎硫平与利培酮治疗晚发精神分裂症患者的临床疗效和安全性。方法:对60例晚发精神分裂症的住院患者随机分为两组,分别用奎硫平和利培酮治疗8周。采用阳性与阴性症状量表(PANSS)评定疗效,用副反应量表(TESS)评定不良反应。结果:奎硫平与利培酮治疗晚发精神分裂症患者的临床疗效差异无显著性。两组不良反应均少而轻。结论:奎硫平治疗晚发精神分裂症疗效好,起效快,不良反应少。
Objective:To compare the efficacy and safety between quetiapinc and risperidone in the treatment of late onset schizophrenia. Method: 60 late onset schizophrenias were randomly divided into two groups. They received quetiapine and risperidone respectively for 8 weeks. The efficacies and side effects were assessed by positive and negative symptom scale (PANSS), treatment emengent symptom scale (TESS). Results:The efficacies of both quetiapine and fisperidone to treat late onset schizophrenias were similar, side effects were fewer and milder, Conclusion: Quetiapine is an effective and safe drug in the treatment of late onset schizophrcnias. Its side effects were fewer.
出处
《临床精神医学杂志》
2006年第1期34-35,共2页
Journal of Clinical Psychiatry
关键词
奎硫平
利培酮
晚发精神分裂症
quetiapine
riperidone
late onset schizophrenia