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口服固体缓控释制剂研究进展 被引量：15

Advances in oral solid controlled-release drug delivery systems
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摘要 近年来,口服缓控释技术发展迅速,种类繁多,其中典型的给药系统包括骨架片、渗透泵制剂、多单元给药系统等。这几类制剂是口服固体缓控释制剂的研究热点和主流,也是与实际生产应用结合最为紧密的制剂类型。本文综述了这几类口服缓控释制剂的最新研究动态。 There are a large number of controlled-release technologies available for dosage form development. Typical oral solid controlled-release drug delivery systems （DDSs） embrace： matrix tablets; osmotic systems, such as the asymmetric membrane technology or swellable core technology; and multiple-unit drug delivery system as well. These DDSs are the hot spot and main trend of oral solid DDSs, and they are tightly integrated with the large-scale production. This review provides the latest advances on these research areas.
作者 李腊蕊 朱家壁
机构地区 中国药科大学药物制剂研究所
出处 《中国药科大学学报》 CAS CSCD 北大核心 2006年第1期14-17,共4页 Journal of China Pharmaceutical University
关键词 口服缓控释 骨架片 渗透泵 多单元给药系统 oral controlled-release matrix tablets osmotic systems multiple-unit drug delivery system
分类号 TQ460.6 [化学工程—制药化工]
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参考文献27

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共引文献78

同被引文献117

引证文献15

二级引证文献53

中国药科大学学报
2006年 第1期

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