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多囊卵巢综合征的卵泡发育异常 被引量:7

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摘要 多囊卵巢综合征(polycystic ovary syndrome,PCOS)是临床常见病、多发病,其病因及病理生理尚有争议。目前的研究认为,PCOS是卵巢病变。PCOS的卵泡发育异常表现有:(1)早期卵泡发育过多;(2)卵泡停滞。引起卵泡过多的因素为卵巢内雄激素过多。卵泡停滞是指无优势卵泡选择。实验证明,卵泡停滞的状态是可以逆转的。优势卵泡的选择与月经前FSH升高,局部的正性、负性选择因子,LH的过早作用及高胰岛素血症和(或)胰岛素抵抗密切相关。PCOS卵泡发育异常表现的两个方面实际上可以全部归结为过多的早期卵泡生长,因为卵泡发育停滞可能是卵泡过多的结果。
出处 《现代妇产科进展》 CSCD 北大核心 2006年第1期64-66,68,共4页 Progress in Obstetrics and Gynecology
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