摘要
目的探讨尿激酶颈动脉注射与静脉注射治疗急性脑梗死的临床疗效,寻求更好的溶栓途径和方法。方法将入选的44例病人随机分为2组,颈动脉注射组(简称A组)21例,将尿激酶30万U稀释,用普通输液针由病灶侧颈动脉穿刺后加压注射;静脉滴注组(简称V组)23例,将尿激酶120万U稀释后静滴。两组辅以相同的常规治疗,14d后观察两组的疗效及不良反应。结果A组:基本痊愈8例(38.1%),显效9例(42.9%),总有效率为95.2%。V组:基本痊愈5例(21.7%),显效6例(26.1%),总有效率82.6%。A组出血1例,发生率为4.8%。V组出血3例,发生率为13.0%。结论尿激酶颈动脉注射的疗效显著高于静脉滴注的疗效(P<0.05)。
Objective To discuss the better ways and the clinic curative effect with UK through the carotid injection and the mainline. Methods 44 patients are divided into two groups, the carotid injection group （A group） 21 cases with 300 ku UK through the focus side carotid and the veining dripping group（A group）23 cases with 1200ku UK through vein dripping, also with general therapy. After 14 clays the clinic curative effect and side-effect are observed. Results in A group, recovey 8 cases（38.1%）, apparent effect 9 cases（42.9%）,the total efficiency is 95.2%. haemorrhage 1 case（4.8%） and in V group, recovery 5 caees（21.7%）, apparent effect 6 cases （21.6%）, the total efficiency is 82.6%, haemorrhage 3 cases （13.0%）. Conclusions It is better clinic curative effect with UK to ACI through carotid injection than through mainline, and haemorrage rate is lower.
出处
《海南医学》
CAS
2006年第3期21-23,共3页
Hainan Medical Journal
