摘要
目的研究新鲜羊膜移植术对治疗早期重发眼烧伤的临床效果。方法采用新鲜羊膜治疗碱烧伤5例(5眼),酸烧伤3例(3眼),热烧伤8例(8眼)。烧伤部位包括角膜、结膜。受伤到手术时间1～14d,平均7d。结果 16眼均无羊膜移植排斥反应和继发感染,眼表稳定。术后3～7d 眼部炎症均可控制,无角巩膜溶解穿孔、虹膜萎缩,视力较前有不同程度提高,其中7眼角膜恢复透明,8眼角膜无新生血管,合并角膜不同程度斑翳,1眼全角膜浑浊。结论运用羊膜移植重建眼表烧伤,可有效促进上皮细胞分化移行,抑制局部炎症,阻止新生血管和瘢痕形成,预防或修复睑球粘连。早期新鲜羊膜移植可用作重度眼烧伤后重建眼表的第一步。
Purpose To investigate the therapeutic effect of fresh amniotic membrane transplantation（AMT） in early stage of severe ocular chemical and thermal burn. Methods Sixthteen patients with ocular burn （ 16 eyes） were treaeted with fresh amniotic membrane transplantation. Of them, there were 5 cases of severe alkali bum （5 eyes）, 3 cases of severe acid burn （3 eyes）, and 8 cases of thermal bum（8 eyes）. Results There was no reject reaction obseved, ocular surface was stable in all eyes. In 16 eyes, ocular inflmnmation was controlled after 3-7 days of surgery, no continued dissolution, perforation and iris atrophy were found. There were corneal transparency in 7eyes, no corneal neovascular in 8 eyes with, corneal macula in 8 eyes and total corneal opacity in 1 eye. Conclusion Fresh amniotic membrane transplantation for ocular surface reconstruction can effectively advance the polarization and migration of epithelium cell, reduce local inflammation reaction, neovascularization and fibrosis. Unpreserved AMT might be an initial intervention for ocular surface reconstruction at early stage of severe eye burns.
出处
《中国眼耳鼻喉科杂志》
2006年第1期34-35,共2页
Chinese Journal of Ophthalmology and Otorhinolaryngology
关键词
羊膜移植
眼烧伤
治疗
amniotic membran transplantation
eye bruns
treatment
