摘要
目的分析阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对高血压患者昼夜血压节律、心律失常及心功能的影响。方法高血压合并OSAHS患者(HT+OSAHS组)86例,单纯高血压患者(HT组)30例,健康组(N组)30例,均行多导睡眠图、动态血压、动态心电图及超声心动图检查,对相关数据进行分析比较。结果HT+OSAHS组夜间收缩压、舒张压平均值均高于HT组及N组,“非杓形”血压节律占61·4%,显著高于HT组的21·2%,N组的1·8%;HT+OSAHS组窦性心动过缓、室性早搏、室性心动过速、Ⅱ°以上房室传导阻滞、心房纤颤、心房扑动、室上性心动过速、心脏肥厚发生率均显著多于HT组及N组,而左室射血分数则低于对照组(P<0·05)。结论阻塞性睡眠呼吸暂停低通气综合征对高血压患者血压高度及昼夜变化、心律失常、心功能状态有显著影响。
Objective To study the effect of obstructive sleep apnea-hypopnea syndrome （OSAHS） on diurnal blood pressure and cardiac arrhythmias in patients of hypertension. Methods Eighty-six patients with hypertension complicated with OSAHS （ HT＋OSAHS group） and 30 patients with hypertension without OSAHS （ HT group） and 30 healthy persons （ N group） were enrolled. All subjects in 3 groups underwent polysomnography（PSG）, ambulatory blood pressure, ambulatory electrocardiogram and echocardiography. Results The night average systolic and diastolic blood pressure （SBP and DBP）are higher in HT＋OSAHS group than that in HT gronp and N group. Non-dipper has been found in 61.4% in HT＋OSAHS group while is markedly higher than that in HT group（ 21.2% ） and N group（ 1.8% ） . Prevalence rates of arrhythmias are significantly higher in HT＋ OSAHS group than that in comparative group, while left ventricular ejection fraction（LVEF） is lower （P〈0. 05） . Conclusion OSAHS has been shown to have significant deteriorative effect on diurnal blood pressure, arrhythmias and cardial function in patients of hypertension.
出处
《高血压杂志》
CSCD
北大核心
2006年第1期33-35,共3页
Chinese Journal of Hypertension
