摘要
目的探讨帕夫林治疗轻型复发性口疮的临床效果和药效机理。方法183例轻型复发性口疮患者分为两组,分别口服帕夫林胶囊、多抗甲素片治疗,观察其治疗效果,并于治疗前、后采用流式细胞术检测患者外周血T淋巴细胞亚群。结果帕夫林治疗组总有效率达80.43%,治疗后CD3‘、CD4‘CD4/CD8升高,CD8降低,与治疗前比较差异有统计学意义;帕夫林疗效优于多抗甲素。结论采用帕夫林胶囊治疗轻型复发性口疮效果肯定,其机理可能为提高了患者的细胞免疫功能。
Objective To evaluate the effect of total glucosides of paeony capsules on treatment of mild type recurrent aphtha ulceration （RAU）. Metheds 183 patients were divided into 2 groups and treated by total glucosides of paeony capsules or polyactin A respectively and the clinical effect was observed. The ratio of T lymphocyte subgroups was examined with flow eytometry. Results In the total glucosides of paeony capsules treated group, the effect rate was 80.43 % and the ratio of patients＇ CD3, CD4, CD4/CD8 increased while the ratio of CD4 decreased remarkably. Condusion The total glucosides of paeony capsules is effective for mild type RAU through regulating the patient＇s cell immtmity function.
出处
《广东牙病防治》
2006年第1期41-42,共2页
Journal of Dental Prevention and Treatment
