摘要
目的:探讨发作间期FDGPET与发作期SPECT脑显像在小儿顽固性癫痫定位诊断中的价值。方法:对30例小儿顽固性癫痫患者行发作间期FDGPET与发作期SPECT显像,并对结果进行对比分析。结果:16例发作间期PET表现为局限性单叶代谢减低,14例表现为多灶或弥漫性改变。发作期SPECT显像18例为单叶局限性高灌注,10例为多处高灌注灶。30例患者中26例(86.7%)两项检查结果相符合,12例PET发作间期呈多病灶或弥漫性改变者,6例于发作期转化为单叶局限性病灶。结论:发作期SPECT结合发作间期PET显像,两者联合应用优势互补,可提高癫痫定位的准确性,为进一步治疗提供更可靠的信息。
Objective： To evaluate the value of interictal PET and ictal SPECT brain imaging in localizing the foci of intractable epilepsy in children. Methods： Thirty pediatric patients with intractable epilepsy were performed with interictal PET and ictal SPECT brain imaging. The results were compared and analysed. Results： In interictal PET, 16 patients showed local single lobe hypo-metabolism, multi-lobe and diffuse hypo-metalism in 14 patients. During ictal SPECT studies, 18 showed hyper-perfusion in solitary lobe, muhi-hyper-perfusion foci in 10 patients. Compared the two examinations, 26（86.7%） were accorded with each other in 30 patients. Of the 12 patients with multiple and diffuse hypometabolism in interictal PET, 6 patients showed foci changed to solitary focal hyper-perfusion in ictal SPECT. Conclusion： Interictal PET combined with ictal SPECT can learn from others＇s strong points to offset one＇s weakness, elevate the accuracy in localizing epileptic loci, offer more reliable messages for treatment.
出处
《中国临床医学影像杂志》
CAS
北大核心
2006年第2期82-84,共3页
Journal of China Clinic Medical Imaging
