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TSG-6和连接蛋白在小鼠卵丘-卵母细胞复合体的共位性分析

Analysis of co-localization of tumor necrosis factor-stimulated gene-6 and link protein in cumulus-oocyte complexes of mouse
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摘要 目的：探讨小鼠卵丘-卵母细胞复合体(COC)中 TSG-6和连接蛋白(LP)与透明质酸(HA)的相关性。方法：应用激光扫描共聚焦显微镜和免疫荧光双重染色技术观察小鼠 COC 中 TSG-6和 LP 的表达和分布。结果： TSG-6和 LP 在 COC 中呈阳性表达。结论：TSG-6和 LP 的阳性表达可能和 HA 在 COC 成熟中起重要作用。 Objective： To investigate the correlationship between tumor necrosis factor-stimulated gene-6 （TSG- 6）, link protein （LP） and hyaluronic acid in the cumulus-oocyte complexes of mice. Methods： Distribution of TSG-6 and LP in the cumulus-oocyte complex was studied with laser confocal microscope and double immunoflu- oresence staining. Results： TSG-6 and LP were expressed in cumulus-oocyte complex of mice. Conclusion： TSG-6 and LP may play an important role in the maturation of cumulus-oocyte complex.
作者 吴吉文 卓丽圣 王玮
机构地区 福建医科大学人体解剖学与组织胚胎学系 日本爱知医科大学分子医科学研究所
出处 《解剖学杂志》 CAS CSCD 北大核心 2006年第1期48-50,71,共4页 Chinese Journal of Anatomy
关键词 卵丘-卵母细胞复合体 TSG-6 连接蛋白 小鼠 cumulus-oocyte complex tumor necrosis factor-stimulated gene-6 link protein mouse
分类号 R321 [医药卫生—人体解剖和组织胚胎学]
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参考文献13

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二级参考文献6

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解剖学杂志
2006年 第1期

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