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结节性硬化症分子生物学研究进展 被引量:6

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摘要 结节性硬化症的分子病理机制尚未完全阐明,其致病基因TSC1和TSC2编码的错构瘤蛋白和结节蛋白具有肿瘤抑制作用,是细胞生长和增殖的重要调节因子。以往对结节性硬化症的研究多关注TSC1和TSC2基因缺失和突变,本文旨在对结节性硬化症的分子生物学研究进展做一综述。
出处 《国外医学(遗传学分册)》 2005年第5期295-298,共4页 Foreign Medical Sciences(Section of Genetics )
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