摘要
目的:观察肺气肿肺气虚证模型大鼠脾脏指数、胸腺指数的变化,探讨其在肺气肿肺气虚证发病中的作用机制。方法:将90只SD大鼠随机分为对照1个月、2个月、3个月组和模型1个月、2个月、3个月组,采用气管内注入脂多糖(LPS)和烟熏双因素复合制作肺气肿肺气虚证大鼠模型,乙醚吸入法麻醉后剥离胸腺和脾脏,电子天平称重。结果:1个月模型组大鼠的脾脏指数和胸腺指数均高于同月对照组,3个月模型组大鼠的胸腺指数和脾脏指数均低于同月对照组,3个月左右模型组大鼠胸腺指数和脾脏指数趋于稳定。结论:肺气肿肺气虚证大鼠脾脏指数与胸腺指数降低,机体免疫功能下降。
Objective： To observe the change on thymus of the lung-qi of pulmonary emphysema, and investigate the with insufficiency of the lung-qi of pulmonary emphysema. index and spleen index in rats with insufficiency relationship between spleen index, thymus index Methods：90 SD rats were randomly devided into control group （1 month, 2 months, 3 months） and model group （1month, 2months, 3months）, made rat models by pouring Lipopolysacchride （LPS） into trachea and putting rats into smoking environment, and anaesthetised with ether, striped the spleen and thymus, and weighted. Results：l month rats＇ spleen index and thymus index in model group were higher than the ones of same month rats in control group, while 3 months rats＇ spleen index and thymus index in model group were lower than the ones of same month rats in control group. Conclusion：The spleen index and thymus index of rats with insufficiency of the lung-qi of pulmonary emphysema decreased and the immune function declined.
出处
《甘肃中医学院学报》
2006年第1期20-22,共3页
Journal of Gansu College of Traditional Chinese Medicine
关键词
肺气肿
肺气虚证
脾脏指数
胸腺指数
pulmonary emphysema
insufficiency of the lung-qi
spleen index
thymus index
