摘要
目的:研究葛芩微囊的制备工艺。方法:采用单凝聚法制备葛芩微囊,通过均匀设计优化葛芩微囊的制备工艺,并进行质量评价。结果:葛芩微囊最佳制备工艺为囊心:囊材=1∶2;成囊温度:55℃;转速:1200r/min。结论:所制得的葛芩微囊,大小与分布、溶出度均符合要求。
Object:To study preparation technique of GeQin microcapsule.Methods:GeQin microcapsule was prepared by simple coacervation method.Using the uniform design,the preparation technique of GeQin microcapsule was optimized,and the quality was evaluated.Results:The optimum preparation technique of GeQin microcapsule:the ratio of core material to coating material was 1:2,the temperature of encapsulation was at 55℃ and the stirring speed was 1200r/min.Conclusion: The results showed that GeQin microcapsule had appropriate diameter and distribution of microcapsule particles size as well as requirements.
出处
《中医药学报》
CAS
2006年第1期6-7,共2页
Acta Chinese Medicine and Pharmacology
基金
哈尔滨市科学研究基金项目(2002AFXXJ028)
关键词
微囊
单凝聚法
均匀设计
Microcapsule
Simple coacervation
Uniform design (Original article on page 6)
