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19例儿童1型糖尿病初发病例甲状腺自身抗体及补体C3的观察 被引量:1

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摘要 目的观察儿童1型糖尿病初发病例血清中的甲状腺自身抗体及补体C3水平情况。方法采集19例儿童1型糖尿病初发病例血清和40例正常儿童血清,利用电化学发光法检测甲状腺球蛋白抗体(TG-Ab)、甲状腺过氧化物酶抗体(TPO-Ab),采用速率散射比浊法检测补体C3。结果糖尿病组的TPO-Ab阳性率明显高于正常组(P<0.01),TG-Ab阳性率与正常儿童无明显差异。糖尿病组C3值明显低于正常组(P<0.01)。结论1型糖尿病和自身免疫性甲状腺疾病同属自身免疫内分泌紊乱,二者之间有一定的联系。补体C3缺陷在儿童1型糖尿病的发病机制中可能具有一定的作用。
出处 《华中医学杂志》 2006年第1期27-28,共2页 Central China Medical Journal
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