期刊文献+

鼻腔给药吸收促进剂的研究进展 被引量:11

下载PDF
导出
摘要 鼻腔给药具有吸收迅速,生物利用度高,给药方便,易于被患者接受等优点,尤其是为蛋白多肽类药物提供了一条可能的非注射给药途径。药物鼻腔给药常需加入吸收促进剂以提高其吸收,本文参阅近期国内外文献对鼻腔给药吸收促进剂的作用机理、毒性及评价方法、增效减毒的方法等进行综述。
出处 《解放军药学学报》 CAS 2006年第1期55-57,共3页 Pharmaceutical Journal of Chinese People's Liberation Army
  • 相关文献

参考文献34

  • 1王东兴,高永良.鼻腔给药新剂型研究进展[J].中国新药杂志,2002,11(8):589-592. 被引量:34
  • 2Illum L.Nasal drug delivery:new developments and strategies[J].DDT,2002,7(23):1184.
  • 3Illum L.Nasal drug delivery-possibilities,problems and solutions[J].J Control Release,2003,87 (1-3):187.
  • 4陈颖,刘娟,汪国华.鼻腔给药系统药用辅料研究进展[J].医药导报,2005,24(4):312-314. 被引量:4
  • 5毛世瑞,杨宏图,毕殿洲.提高药物鼻粘膜吸收的途径[J].中国药学杂志,1998,33(11):641-645. 被引量:15
  • 6Chavanpatil1 M D,Vavia P R.The influence of absorption enhancers on nasal absorption of acyclovir[J].Eur J Pharm Biopharm,2004,57(3):483.
  • 7Merkus,F.W.Interspecies difference in the nasal absorption of insulin[J].Pharm.Res,1991,8(10):1343.
  • 8史振祺,蒋新国.磷脂类衍生物作为鼻粘膜药物吸收促进剂的应用[J].国外医学(药学分册),2003,30(4):241-245. 被引量:4
  • 9Chandler SG,Illum L,Thomas NW.Nasal absorption in rats:effect of enhancers on insulin absorption and nasal histology[J].Int J Pharm,1991:76(1-2):61.
  • 10Sinswat P,Tengamnuay P.Enhancing effect of chitosan on nasal absorpton of salmon calcitonin in rats:comparison with hydroxypropyland dimethyl-cyclodextrins[J].Int J Pharm,2003,257(1-2):15.

二级参考文献108

  • 1董泽民.赖氨匹林脂质体鼻腔给药的研究[J].中国医药工业杂志,1995,26(5):199-202. 被引量:18
  • 2蒋新国,崔景斌,方晓玲,韦阳,奚念朱.药物的鼻粘膜纤毛毒性及评价方法[J].药学学报,1995,30(11):848-853. 被引量:86
  • 3陆翔 蒋新国 等.促进剂对大鼠鼻粘膜药物吸收的影响[J].上海医科大学学报,1996,23:49-49.
  • 4Illum L,Farraj NF,Critchley H,et al.Enhanced nasal absorption of insulin in rats using lysophosphatidycholine[J].Int J Pharm,1989,57(1):49-54
  • 5Marlin GP, Marriott C, Kellaway IW.Direct effect of bile salts and phospholipids on the physical properties of mucus[J]. Cut, 1978, 19(2) : 103- 107.
  • 6Illum L, Fisher AN, Jabbed-Gill I,et al. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides[J]. Int J Pharm, 2001, 222(1):109-119.
  • 7Illum L,Farraj NF,Davis SS,et al.Investigation of the nasal absorption of biosynthetic human growth hormone in sheep-use of a bioadhesive microsphere delivery system[J].Int J Pharm,1990,63(3):207-211
  • 8Chandler SC,, Thomas NW, Illum L. Nasal aimrption in the rat,Ⅲ. Effect of lysophospholipids on insulin absorption and nasal histology[J].Pharm Res, 1994, 11(11):1623- 1630.
  • 9Gould LA,Lansley AB, Brown MB,et al.Mitigation of surfactant erythrocyte toxicity by egg phosphatidylcholine[J].erythrocyte toxicity by egg phosphatidylcholine[J].J Pharm Pharmacol,2000,52(10):1203-1209
  • 10Martini A, Artico R, Civaroli P,et al. Critical micellar concentration shifting as a simple tool for evaluating cyclodextrin/enhancer interations[J].Int J Pharm,1996,127(2):239-244

共引文献165

同被引文献231

引证文献11

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部