摘要
目的建立片仔癀(牛黄,三七,蛇胆、麝香等)的质董标准。方法采用薄层色谱法对处方中牛黄、三七、蛇胆进行定性鉴别;用气相色谱法测定麝香酮的舍量。结果在TLC定性鍪别图谱中三七、牛黄及蛇胆的分离度好,专属性强;麝香酮在0.0044-0.43μg进样范围内具有良好的线性关系,相关系数r=0.9995.平均加样回收率为99.58%,RSD为3.10%(n=9)。结论谊方法简便、准确,重复性好,可用于片仔癀的质量控制。
OBJECTIVE To establish a quality standard for Pianzihuang. METHODS Calculus Bocis,Radix Notoginseng, Snake's gallbladder in Pianzihuang were identified by TLC. The content of muscone was determined by GC. RESULTS Calculus Boeis, Radix Notoginseng,Snake's gallbladder could be identified by TLC;Muscone showed a good linearity relationship in the range of 0. 0044-0.43ug. The average recovery was 99.58% and RSD was3.10%. CONCLUSION The method are available with a reproducibility and could control the quality of this preparation effectively.
出处
《海峡药学》
2006年第1期24-28,共5页
Strait Pharmaceutical Journal
关键词
片仔癀
牛黄
三七
蛇胆
麝香
麝香酮
气相色谱法
Pianzihuang
Calculus Bocis
Radix Notoginseng
Snake's gallbladder
Moschus
Muscone
GC