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围产期解脲支原体感染与早产关系的研究 被引量:4

A Prospective Study on Relationship between Genital Ureaplasma Urealyticum Infection during Perinatal Period and Preterm Labor
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摘要 目的探讨孕妇生殖道解脲支原体感染与早产的关系。方法随机入选的1240例孕妇,采用支原体培养法检测围产期孕妇宫颈分泌物中的解脲支原体,根据检测结果分为支原体阳性组和支原体阴性组,随访观察两组早产的发生率。结果解脲支原体阳性组550例,解脲支原体阴性组690例,阳性组早产发生率为6.2%(34/550),阴性组2.2%(15/690),前者显著高于后者(P〈0.05);队列研究显示孕期解脲支原体感染显著增加早产的危险性(RR为2.82,95%CI为1.57-5.17,P〈0.05)。结论孕妇生殖道解脲支原体感染可导致早产的发生。 Objective To investigate the relationshipm between genital Ureaplasma urealyticum infection during perinatal period and preterm labor. Methods 1240 cases of pregnant women were randomly enrolled into this study. Vaginal Ureaplasma urealyticum were detected by the mycoplasma culture during perinatal period. All women were divided into group Ureaplasma urealyticum positive and group Ureaplasma urealyticum negative, and the incidence rate of the preterm labor was followed up. Results The preterm labor incidences in group Ureaplasms urealyticum-positive( n = 550) and group Ureaplasma urealyticum negative( n = 690) were 6.2% and 2.2% , respectively, the former being significantly higher than the latter (P 〈 0.05). The cohort study showed that Ureaplasma urealyticum infection in pregnency significandy increased the risk of preterm labor. (RR = 2.82, 95 % CI: 1.57- 5.17, P 〈 0.05). Conclusion Ureaplasma urealyticum infection during perinatal period may play an adverse role in preterm labor.
出处 《同济大学学报(医学版)》 CAS 2006年第1期71-72,共2页 Journal of Tongji University(Medical Science)
基金 上海市卫生局基金资助项目(wsj99436)
关键词 解脲支原体 早产 围产期 生殖道 Ureaplasma urealyticum preterm labor perinatal period
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参考文献5

  • 1Cassell GH,Waites KB,Crouse DT.Perinatal mycoplasma[J].Clin Perinatal,1991,18(2):241.
  • 2郑怀美.妇产科[M].北京:人民出版社,1992..
  • 3Mcdonal HM,O'loughlin JA,Jolly P.Prental microbiological risk factors associated with acute respiratory insufficiency and death in premature infants[J].J Pediatr,1993,122(5):756.
  • 4Ollikainen J,Hiekkaniemi H,Korppi M,et al.Ureaplasma urealyticum infection associated with acute respiratory insufficency and death in premature infants[J].Pediatr,1993,122(5):756.
  • 5Carey JC,Blackwelder WC,Nugent RP,et al.Antepartum cultures for Ureaplasma are not useful in predicting pregnancy outcomes[J].Acta padiatr,1993,82(2):198-200.

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