摘要
目的评价无抽搐电休克治疗与选择性5-羟色胺再摄取抑制剂治疗抑郁症的疗效及对记忆的影响.方法 60例抑郁症患者随机分成两组,分别实施无抽搐电休克治疗(MECT)及选择性5-羟色胺再摄取抑制剂(SSRI)治疗,采用汉密顿抑郁量表(HAMD)、修订韦氏记忆量表(WMS)分别评定2组的疗效及对记忆的影响.结果无抽搐电休克治疗与SSRI总体疗效相当,但无抽搐电休克治疗起效更快.无抽搐电休克治疗对记忆有影响,但在1～2周内逐渐得到恢复.结论无抽搐电休克治疗是一种值得推广的安全有效的治疗抑郁症的方法.
Objective To compare the efficacy and the influence on memory between modified-ECT （MECT） and selective serotonin reuptake inhibitors （SSRT） in the treatment of depression. Methods 60 inpatients with depression were randomly assigned into MECT group and SSRT group. The effects and the influences on memory were evaluated with Hamilton depression scale （HAMD） and Wechsler memory scale （WMS） before and after the treatment. Results Findings indicated that efficacy of MECT was similar to that of SSRT, however MECT took effect more quickly. MECT has a little effect on memory; the period of recovering the memory in MECT group was about 1- 2 weeks. Conclusions MECT is effective and safe in the treatment of depression, it is valuable to be recommended clinically.
出处
《神经疾病与精神卫生》
2005年第6期424-426,共3页
Journal of Neuroscience and Mental Health
关键词
无抽搐电休克治疗
抑郁症
记忆
Modified electric shock therapy Depression Memory
