摘要
应用微量输液泵持续静脉输注吗啡（ＣＩＭ）进行腹部手术后镇痛的前瞻性临床研究，４０例腹部大中手术患者随机分入两组，实验组接受ＣＩＭ法镇痛，对照组采用常规间断肌注哌啶镇痛（ＩＭＰ）。实验组２０例术后２４ｈ内镇痛效果均达Ⅰ～Ⅱ级，而对照组肌注哌啶后２ｈ内有７０％患者达Ⅰ～Ⅱ级，仅１０％患者在肌注２ｈ后仍保持Ⅰ～Ⅱ级的镇痛效果。实验、对照组患者术后２４ｈ睡眠时间分别为６．２±１．９ｈ和４．０±１．２ｈ（Ｐ＜０．０１）。ＣＩＭ法术后肠道通气时间短于ＩＭＰ法，分别为５４±１３ｈ和６６±１１ｈ（Ｐ＜０．０１）。两组呼吸频率、心率、血压、ＳｐＯ＿２等无明显差别。结果表明，微量泵持续静脉输注吗啡法镇痛效果优于常规方法，是一种简便、安全、有效的术后镇痛方法。
This study was designed as a prospective randomized comparative trial of continuous infusion of morphine(CIM) controlled by a micro-electric pump and traditional intermitted intramuscle injection of pethidine (IMP) to relieve pain after surgery.40 patients submitted from upper abdominal surgery were divided into two groups ,20 patient recieving CIM and others using IMP. The amount of morphine used during the 24 hours was 0. 5 mg/kg in CIM group. In IMP group, 20 patients were given standard intramuscular dosages of 1. 5mg/kg of pethidine,then,every 4-6 hours repeatedly within 24 hours after operation. An analgesic scale was observed by WHO's pain score from Ⅰ to Ⅳ degree. The result showed that all patients of CIM group had good analgesic effect (ⅠandⅡ degree) ,howerer, 10% of the patients in IMP group had only analgesic effect of Ⅰand Ⅱ degree during the first 24 hours after operation. Their respiratory frequency,heart rate, BP and SpO_2 had no significant difference in two groups. It woule appear that CIM is an efficacious and safe method for providing postoperative pain relief.
出处
《中华护理杂志》
CSCD
北大核心
1996年第2期73-75,共3页
Chinese Journal of Nursing
关键词
腹部外科手术
手术后
吗啡
镇痛
Morphine
Postoperative pain relief
Microelectric infusion pump
