摘要
目的通过调查具不良生活习惯如抽烟、喝酒者胃蛋白酶C基因多态性分布情况,研究生活习惯与胃癌病因之间的关系。方法采用PCR检测具不良生活习惯者中胃蛋白酶原C基因的多态性。结果既抽烟又喝酒者52人中,等位基因1出现频率比对照组高且差异有统计学意义(P<0.05)结论既抽烟又喝酒者是胃癌发病的高危险人群。
Objective To study the relationship between the life habit and the cause of the stomach cancer , through investigation about polymorphism of pepsinogen C gene among the persons with bad life habit, such as smoking and drinking. Methods By means of PCR to detect polymorphism of pepsinogen C gene of the subjects. Results Allele Ⅰ showed higher frequency in those people （52 cases ） who were smoker and drinker than thai in the contrast group （X^2 = 5.58, P 〈 0.05 ）. Conclusion Those people who smoke and drink are more easily suffered from stomach cancer.
出处
《现代肿瘤医学》
CAS
2006年第3期318-319,共2页
Journal of Modern Oncology
基金
湘南学院课题资助项目(项目编号04Y017)
