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食管pH值监测观察酸相关疾病103例 被引量:1

Analysis of one hundred-three acid-related patients by 24-hour esophageal pH monitoring
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摘要 目的探讨24小时食管pH值监测在诊断上消化道疾病中(尤其胃食管反流病)的临床意义。方法对2001年4月~2004年5月于我院进行食管pH值监测的103例临床患者,根据有无症状分为两组,无症状组20例为对照组,有症状组83例,其中反流性食管炎(RE)并慢性胃炎的患者30例,占36.1%,然后依次为十二指肠溃疡19例(22.9%)、非糜烂性食管炎13例(15.6%)、单纯反流性食管炎11例(13.3%)及胃溃疡10例(12.0%)。结果RE并十二指肠溃疡组在各项指标中均高于其他各组(P<0.05)。结论RE多合并其他上消化道疾病(尤其酸相关疾病)发生,罹患十二指肠溃疡可能是RE发生和加重的原因之一。 Objective To study the clinical value of 24-hour pH monitoring in patiens with upper gastrointestinal diseases(especially gastroesophageal reflux disease) .Methods One hundred and three patients were enrolled from April 2001 to May 2004 in our hospital. Twenty four-hour esophageal pH monitoring was used. All patien were divided into two groups : control group(without symptom; n = 20)and experiment group (with symptom; n = 83 ) which included both reflux esophagitis and chronic gastritis ( n = 30, 36.1% ), duodenal ulcer ( n = 19, 22.9% ), non-erosive esophagitis ( n = 13, 15.6% ), reflux esophagitis( n = 11,13.3 % )and gastric ulcer( n = 10, 12.0% ). Results pH and reflux times were highest in patients with both reflux esophagitis and duodenal ulcer ( P 〈 0.05). Conclusion Reflux esophagitis is often accompanied with other upper gastrointestinal diseases (especially disease correlate to acid). Duodenal ulcer may be one of the causes of reflux esophagitis.
出处 《胃肠病学和肝病学杂志》 CAS 2006年第1期71-72,共2页 Chinese Journal of Gastroenterology and Hepatology
关键词 胃食管反流 食管PH值监测 诊断 上消化道疾病 Gastroesophageal reflux Esophageal pH monitoring Diagnose
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参考文献3

  • 1Achem SR.Endoscopy-negative gastresophageal reflux disease.The hypersensitive esophagus.Gastroenterol Clin of North Am,1999,28 (4):893-904.
  • 2李兆申,朱爱勇,邹多武,于凤海,王雯,尹宁,许国铭.反流性食管炎食管内pH值与胆汁反流的关系[J].解放军医学杂志,2000,25(5):316-318. 被引量:12
  • 3Nehra D,Howell P,Williams CP,et al.Toxic bile acids in gastro oesophasgeal reflux disease:influence of gastric acidity.Gut,1999,44(5):598-602.

二级参考文献3

  • 1潘国宗,中华消化杂志,1999年,19卷,223页
  • 2李兆申,解放军医学杂志,1997年,22卷,259页
  • 3许国铭,解放军医学杂志,1997年,22卷,313页

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