期刊文献+

前列腺液白细胞计数与临床症状的相关分析 被引量:45

Analysis of the correlation between expressed prostatic secretion leukocyte counts and the severity of symptom in chronic prostatitis
原文传递
导出
摘要 目的分析慢性前列腺炎(CP)患者前列腺液(EPS)中自细胞(WBC)计数与症状严重程度的关系。方法调查2004年9月至2005年4月CP患者1426例。年龄14~68岁,平均33岁。病程3个月~0年,平均20个月。应用国际前列腺炎症状评分表(NIH—CPSI)测评症状严重程度,EPS常规化验计数WBC数目。对EPS中WBC计数、有无脓细胞与CPSI评分的关系进行统计学分析。结果1426例中非炎症组(EPS中WBC〈10个/HP)357例,炎症组1069例(EPS中WBC≥10个/HP),2组的CPSI总评分分别为20.55±6.17和19.89±7.26,P〉0.05。炎症组1069例按EPS中WBC计数又分为4组,分别为10—20、21—30、31—40、〉40个/HP,4组分别377、392、240、60例,CPSI评分分别为19.40±7.59、20.04±7.14、20.68±7.20、18.82±6.05,P〉0.05。EPS中有脓细胞者CPSI评分为20.77±6.98,无脓细胞者为19.40±7.00,P〉0.05。结论CP患者前列腺内炎症程度与临床症状无平行关系,CP的各种症状表现是多种致病因素、多种发病机制作用的结果。 Objective To investigate the correlation between expressed prostatic secretion (EPS) leukocyte counts and the severity of symptoms in chronic prostatitis (CP). Methods This series included 1426 patients ( age range, 14 - 68 years ;mean age,33 years) with CP from September 2004 to April 2005. The disease course ranged from 3 months to 20 years with a mean of 20 months. The NIH-CPSI was used to determine the symptom severity, and the leukocyte counts in EPS were counted. The correlation of white blood cell count (WBC) and presence or absence of pyocytes with CPSI scores was statistically analyzed. Resuits Among the 1426 patients,non-inflammatory group consisted of 357 cases (WBC in EPS 〈 10/HP), and inflammatory group,1069 cases (WBC in EPS ≥ 10/HP). The overall NIH-CPSI scores of the 2 groups were 20.55 ± 6.17 and 19.89 ± 7.26, respectively (P 〉 0.05 ). According to the WBC in EPS, the inflammation group was subdivided into 4 groups, ie, 10 - 20,21 - 30,31 - 40 and 〉 40/HP groups, whose CPSI scores were 19.40 ± 7.59,20.04 ± 7.14,20.68 ± 7.20 and 18.82 ± 6.05, respectively ( P 〉 0.05 ). The CPSI scores of patients with and without pyocytes in EPS were 20.77 ± 6.98 and 19.40 ± 7.00, respectively (P 〉 0.05). Conclusions Inflammation of the prostate may not be the only cause of various symptoms in CP patients. Many other factors may be involved,and other mechanisms can be used to explain the clinical manifestations of CP.  
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2006年第3期194-196,共3页 Chinese Journal of Urology
基金 国家自然科学基金资助项目(30471724)
关键词 前列腺炎 白细胞 症状 Prostatitis Leukocyte Symptom
  • 相关文献

参考文献8

  • 1Wesselmann U.Neurogenic inflammation and chronic pelvic pain.World J Urol,2001,19 :180-185.
  • 2Litwin MS,McNaughton-Collins M,Fowler FJ Jr,et al.The National Institutes of Health chronic prostatitis symptom index:development and validation of a new outcome measure.Chronic Prostatitis Collaborative Research Network.J Urol,1999,162:369-375.
  • 3Ludwig M,Schroeder-Printzen I,Ludecke G,et al.Comparison of expressed prostatic secretions with urine after prostatic massage-a means to diagnose chronic prostatitis/inflammatory chronic pelvic pain syndrome.Urology,2000,55:175-177.
  • 4Schaeffer AJ,Knauss JS,Landis R,et al.Leukocyte and bacterial counts do not correlate with severity of symptoms in men with chronic prostatitis:The National Institutes of Health Chronic Prostatitis Cohort Study.American Urological Association,Inc.2002,168:1048-1053.
  • 5Potts JM.Chronic pelvic pain syndrome:a non-prostatocentric perspective.World J Urol,2003,21:54-56.
  • 6Nickel JC,Alexander RB,Schaeffer AJ,et al.Leukocytes and bacteria in men with chronic prostatitis/chronic pelvic pain syndrome compared to asymptomatic controls.J Urol.2003,170:818-822.
  • 7True LD,Berger RE,Rothman I,et al.Prostate histopathology and the chronic prostatitis/chronic pelvic pain syndrome:a prospective biopsy study.J Urol,1999,162:2014-2018.
  • 8Propert K J,Alexander RB,Nickel JC,et al.Design of a multi-center randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.Urology,2002,59:870-876.

同被引文献394

引证文献45

二级引证文献334

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部