摘要
目的研究血浆内皮素(ET)和一氧化氮(NO)在颈动脉粥样硬化(AS)中的作用。方法用颈动脉超声检测患者颈AS情况,同时测定血浆ET和NO水平。结果颈AS阳性患者血浆ET水平明显升高,NO水平较阴性患者明显降低。结论AS病变可引起血管内皮依赖性舒张功能障碍,NO降低,ET增高是导致或加重AS的重要因素之一。
Objective To research the effect of plasma endothelin on carotid atherosclerosis. Meth- ods Carotid ethnography was used to observe patient＇s atherosclerotic complexion, and measure the level of plasma endothelin. Results The level of plasma endothelin in carotid atherosclerosis patients is evidently higher than patients without carotid atherosclerosis, but the level of plasma nitric oxide （NO） in carotid atherosclerosis patients was decreased markedly. Conclusion Atherosclerosis can cause blood vessel endothelium dependent diastolic dysfunction. Ascent of endothelin level and descent of NO level may be some of main factors which induce or aggravate artherosclerosis.
出处
《咸宁学院学报（医学版）》
2006年第1期9-10,共2页
Journal of Xianning Univarsity(medical Sciences)
