摘要
目的探讨美托洛尔在儿童血管迷走性晕厥(VVS)中的疗效。方法将直立倾斜试验(HUT)阳性的VVS患儿29例随机分为治疗组(n=16,应用口服美托洛尔治疗)及对照组(n=13,应用复合维生素B或谷维素治疗),观察两组患儿临床晕厥发作次数及HUT结果。结果治疗组无发作9例,发作次数减少5例,发作次数增加、无变化各1例;复查HUT 6例转阴。对照组无发作1例,好转5例,发作次数增加3例,无变化4例;HUT 3例转阴。结论口服美托洛尔可有效治疗儿童VVS。
Objective To explore the effect of the β-blocker--metoprolol on the treatment of vasovagal syncope（WS） in children, Methods Twenty-nine children with unexplained syncope and positive responses to head-up tilt test（HUT） were included in the study.Sixteen of them rook metoprolol （treatment group） and 13 of them took vitamin B or oryzanol （control group） at least 2 weeks and HUT were repeated and syncope episodes were observed. Results In treatment group, 9 of 16 patients had no syncope episode while 5 of 16 patients had fewer syncope episodes, 1 ease had more syncope episodes,and 1 case remained the same. HUT were repeated and 6 of 9 eases had negative outcome. In control group, 1 of 13 patients had no syncope episode while 5 of 13 patients had fewer syncope episode, 3 eases had more syncope episodes and 4 cases remained the .same. HUT were repeated and 3 of 7 eases had negative outcome. Conclusion These results indicate that adminstering metoprolol orally may he effective for WS in children.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2006年第5期305-306,共2页
Journal of Applied Clinical Pediatrics
基金
"十五"国家科技攻关计划项目资助(2004BA720A10)
首都医学发展科研基金项目资助(2002-3037)
