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Amplatzer房间隔封堵器治疗房间隔缺损近期疗效观察

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摘要 目的观察Amplatzer房间隔封堵器(ASO)治疗继发孔型房间隔缺损(ASD)的有效性和可行性。方法在透视及经胸超声心动图(TTE)监视下经导管置入ASO治疗继发孔型房间隔缺损30例,术后包括心电图和TTE在内的临床随访6个月,评价治疗效果。结果30例患者TTE测定ASD直径(22．9±6．3)mm,球囊伸展直径为(23．8±6．7)mm,29例患者封堵成功,置入ASO直径 (25．8±7．2)mm。术后即刻超声提示48．3％患者有微量或少量分流,3 d后复查降至20．7％,1个月后无分流。术前肺动脉收缩压(PASP)为(46．5±10．7)mm Hg(1 mm Hg=0．133 kPa),术后6个月为 (30．2±9．6)mm Hg,术前右室舒张期内径(RVDD)为(48．5±7．0)mm,术后6个月为(35．9±8．1)mm (P<0．01)。术前心功能NYHA分级(1．9±0．5)级,术后6月提高到(1．2±0．4)级。术后无新的心律失常出现,无血栓栓塞发生,无溶血和心内膜炎,无封堵器移位和脱落,无房室瓣功能障碍。结论经导管置入ASO治疗继发孔型房间隔缺损安全有效,近期疗效满意。
作者 胡江飚 傅国胜 徐耕 游向东 马骥 单江
机构地区 浙江大学医学院附属第二医院心内科
出处 《中国医师进修杂志（内科版）》 2006年第3期59-60,共2页 Chinese Journal of Postgraduates of Medicine
关键词 房间隔缺损 AMPLATZER封堵器 介入治疗
分类号 R654.2 [医药卫生—外科学] R734.205 [医药卫生—肿瘤]
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参考文献4

  • 1Fischer G , Stieh J, Uebing A, et al. Experience with transcatheter closure of secundum atrial septal defects using the Amplatzer septal occluder: A single center study in 236 consecutive patients. Heart,2003,89 : 199 - 205.
  • 2李田昌,胡大一,边红,庞文跃,彭建军,卢长林.Amplatzer房间隔封堵器治疗房间隔缺损[J].中国医药导刊,2003,5(3):182-184. 被引量：4
  • 3Varma C, Benson LN, Silversides C, et al. Outcomes and alternative techniques for device closure of the large secundum atrial septal defect. Catheter Cardiovasc Interv,2004,61 : 131 - 139.
  • 4Hill SL ,Berul CI,Patel Hl,et al. Eatly ECG ahnormalities associated with tranacatheter closure of atrial septal defects using the Amplatzer(R) septal occluder. Journal of Interventional Cardiac Electrophysiology, 2000,4 : 469 - 473.

二级参考文献10

  • 1Brockmeier K, Schmidt KG, Ulmer HE, et al. Occlusion of interatrial communications with the Amplatzer device: experieace in 48 consecutive patients. J Interv Cantiol,2001; 14(3) :325- 328.
  • 2Krumsdorf U, Keppeler P, Horvath K, et al.Catheter closure of atrial septal defects and patent foramen ovale in patients with an atrial septal aneurysm using different devices. J Interv Cardiol, 2001; 14(1) :49 - 55.
  • 3Omeish A, Hijazi ZM. Transcatheter closure of atrial septal defects in children & adults using the Amplatzer Septal Occluder. J Interv Cardiol, 2001 ; 14(1) : 37 - 44.
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  • 6Thomson JD, Aburawi EH, Watterson KG, et al.Surgical and transcatheter (Amplatzer) closure of atrial septal defects: a prospective comparison of results and cost. Heart, 2002;87(5) :466-469.
  • 7Brandt RR, Neumann T, Neuzner J, et al. Transcatheter closure of atrial septal defect and patent foramen ovale in adult patients using the platzer occlusion device: No evidence for thrombus deposition with an-tiplatelet agents. J Am Soc Echocardio-r, 2002:15(10) : 1094- 1098.
  • 8Du Z, Koenig P, Cao Q, et al. Comparison of -ter closure ofsecundum atrial septal defect using the Amplatzer septal occluder as-sociated with deficient versus sugiciem rims. Am J Cardiol, 2002 ;9o(8) :865.
  • 9Du ZI), Cao QL, Rhodes J, et al. Choice of device si- and resultsof mmscatheter closure of atrial septal defect using the amplatzerseptal occluder. J lnterv Cardiol, 2002; 15(4) :287 - 292.
  • 10Acar P, Aggoun Y, Abdel- Massih T. Images in cardiology:3hr-mbus after wanscatheter closure of ASD with an Araplat-er septaloccluder assessed by three dimensional echocardiographic reamstn-tion. Heart, 2(- ;88(1):52.

共引文献3

中国医师进修杂志（内科版）
2006年 第3期

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