摘要
目的探讨老年原发性高血压(EH)患者脉压(PP)与同型半胱氨酸(Hcy)的关系。方法369例EH老年患者进行体检,检测血清Hcy及其他生化指标。依据PP的大小分为3组行组间对照,比较不同PP、血压组间血清Hcy浓度。结果EH患者PP和Hcy之间密切相关,在对高血压的其他危险因素进行调整后,这种相关性仍然存在。结论老年EH患者PP升高与Hcy升高密切相关。Hcy可能参与了EH的发生与发展。
Objective To investigate the relationship between circulating levels of homocysteine （Hcy）and pulse pressure（PP） in old patients with essential hypertension（EH）. Methods A total of 369 old subjects were sampled from out-patients and in-patients. The concentrations of homocysteine, serum triglyceride, LDL cholesterol, HDL cholesterol and glucose were measured. Results A positive relationship was found between PP and Hcy（ P 〈 0. 001 ）. This relationship remained after adjustment for classical EH risk factors. Conclusions Increase in PP is associated with elevated Hcy levels in old patients with EH. Hey might play an important role in the pathogenesis of essential hypertension.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2006年第1期16-18,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
山西省教育委员会科技项目(200104)
