摘要
肝细胞生长因子是一种对神经系统有较强营养作用的细胞因子,对中枢和周围神经元的生长、分化、修复和再生起重要作用。近年来的研究表明,肝细胞生长因子与多种神经系统疾病,如脑缺血、运动神经元病、神经胶质瘤、Alzheimer病等的发生发展密切相关。文章综述了肝细胞生长因子在神经系统疾病中的表达和作用。
Hepatocyte growth factor (HGF) is a potent neurotrophic cytokine in the nervous system. It plays important roles in central and peripheral neuronal growth, differentiation, repair, and regeneration. The recent studies have shown that HGF has close correlation with a number of nervous system diseases in their occurrence and development, such as cerebral ischemia, motor neuron disease, glioma, and Alzheimer's diseases. The article reviews the expression and effect of HGF in nervous system diseases.
出处
《国外医学(脑血管疾病分册)》
2005年第12期933-937,共5页
Foreign Medical Sciences Cerebrovascular Diseases