摘要
目的评价室间隔化学消融术治疗肥厚梗阻型心肌病在急性期的效果。方法对52例确诊肥厚梗阻型心肌病患者进行经皮室间隔化学消融术治疗,并于术前、术后急性期进行超声心动观察。结果41例患者介入治疗成功,成功率为78.8%。术前超声观察室间隔平均厚度(22.96±5.15)mm,左室流出道压力阶差(LVOTPG)(92.64±38.69)mm Hg(1mm Hg=0.133kPa),术后急性期(4.8±3.2)d,室间隔平均厚度(21.27±4.64)mm,较术前比变薄,P<0.05;LVOTPG(51.79±38.99)mm Hg,较术前明显降低,P<0.001。结论经皮室间隔化学消融术治疗肥厚梗阻型心肌病,在急性期可使室间隔平均厚度降低,收缩期左室流出道压力阶差显著下降。
Objective Gauging the acute effect of Percutaneous transluminal septal myocardial ablation （PTSMA） as a treatment for hypertrophic obstructive cardiomyopathy （HOCM）. Methods PTSMA was performed in 52 patients with symptomatic HOCM [mean age （44. 7 ± 11.9） , male 38, female 14]. All patients had echocardiagraphy performed prior to the procedure, 3 -7 days post-PTSMA. Results Procedure success was achieved in 41 patients, success rate was 78. 8%. The average left ventricular outflow tract （LVOT） gradient was （92. 64 ± 38. 69） mm Hg before the procedure, and （51.79 ± 38.99） mm Hg after the procedure （ P 〈 0. 001 ）. The thickness of interventricular septum （ IVS ） was （22. 96 ± 5. 15） mm before the procedure and became （21.27 ±4. 64）mm 3 -7 days post-PTSMA （P 〈0. 05）. The incidence of fight bundle branch block development post-PTSMA was 15. 38% （ 〉48 h）, and one patient （1.92%） had complete heart block. Two patients died. Conclusion PTSMA is an effective non-surgical procedure for symptomatic patients with HOCM because of its low risk and its significant hemodynamic and echocardiographic improvement.
出处
《中华内科杂志》
CAS
CSCD
北大核心
2006年第3期210-212,共3页
Chinese Journal of Internal Medicine
