摘要
目的制定适合我国阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的生命质量评估表并做初步检验。方法通过与OSAHS相关人员访谈并参考国外OSAHS生命质量量表确立反映OSAHS生命质量的条目库。由20例OSAHS患者对条目库进行筛选,计算频度、重要性评分和影响分,将影响分大于1.5分的条目纳入量表。对52例OSAHS患者根据呼吸紊乱指数(AHI)分为AHI<40与AHI≥40两组,比较两组生命质量评分,其中20例在第1次生命质量测评后的1周内进行了重测,计算两次测评的相关性。结果条目库共有72个条目,从中筛选出影响分大于1.5分的条目37条,其中症状12条、日常工作生活6条、社会关系5条、警觉6条、情感8条,加上一个对自我总体生命质量评价的条目,最终形成含5个维度,37+1个条目的正式量表。AHI<40与AHI≥40两组生命质量评分比较,无论是总分还是各维度分,AHI<40组明显高于AHI≥40组(P<0.01)。1周内的重测结果显示,量表总分和上述5个维度的重测相关系数分别为0.885、0.840、0.798、0.928和0.842。结论本量表具有较好的信度和效度,可作为我国OSAHS成人患者生命质量的测评工具。
Objective To develop an instrument to measure the quality of life （QOL） suitable for Chinese adult patients with obstructive sleep apnea hypopnea syndrome （OSAHS） and evaluate it. Methods A list of 72 items potentially related to QOL of patients with OSAHS was constructed via discussion with OSAHS related people, as well as referring to some foreign QOL instruments. Twenty patients were asked to identify the most significant items. Then, frequency, importance and impact score, which is the product of frequency and importance, of the items were calculated. Those items with an impact score equal to or greater than 1.5 were retained in the instrument. Fifty-two OSAHS patients were divided into two groups based on their apnea-hypopnea index （AHI） （AHI 〈40 and AHI≥40） and the QOL scores were compared between the two groups. The QOL of 20 among 52 patients were revaluated in a week and test-retest coefficient was calculated. Results Thirty-seven items associated with an impact score equal to or greater than 1.5 were retained in the instrument and clustered into five domains, i. e. , symptoms （ 12 items）, daily functions （6 items）, interpersonal relationships （ 5 items）, vigilance （ 6 items ） and emotions （ 8 items ）. All those 37 items plus one item of overall evaluation of QOL formed the QOL-OSAHS instrument. The test-retest coefficient of the instrument was 0. 885, 0. 840, 0. 798, 0. 928 and 0. 842 for overall score and the score in five domains, respectively. Score of QOL was significantly higher in the OSAHS patients with AHI 〈 40 than those with AHI ≥ 40 measured by the instrument, both in overall score or score of varied domains （ P 〈 0. 01 ）. Conclusion The QOL-OSAHS instrument is of reasonable reliability and validity and can be served to measure and evaluate QOL for Chinese adult OSAHS patients.
出处
《中华全科医师杂志》
2006年第3期150-153,共4页
Chinese Journal of General Practitioners
关键词
睡眠呼吸暂停低通气综合征
生活质量
量表
Obstructive sleep apnea hypopnea syndrome
Quality of life
Instrument
