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总胆红素 白蛋白比值胆红素神经毒性关系探讨 被引量:3

Clinical Significance between TB/A ratio and Bilirubin Encephalopath
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摘要 目的研究血清总胆红素/血浆白蛋白比值(TB/A)与脑干听觉诱发电位(BAEP)的关系,并探讨其在胆红素神经毒性中的临床意义。方法根据BAEP表现,将70例足月非溶血性高胆红素血症患儿分成A、B、C三组,检测三组患儿血清总胆红素(TB)、血浆白蛋白(A)的值,分析总胆红素/白蛋白(TB/A)与BAEP的相关性。结果C组TB及TB/A比值均明显高于A、B两组,TB/A比值与BAEP异常密切相关。结论TB/A比值可作为预测高胆红素血症对中枢神经系统损伤的良好指标。 Objective To investigate the relationship between the total bilirubintoil/albumin (TB/A) ratio and brainstem auditory evoked potential( BAEP), and its clinical significance in bilirubin encephalopathy. Methods 70 full term newborns with hyperbilirubinmia were divided into 3 groups according the results of BAEP: group A, B and C. Total bilirubintoil (TB) and albumin (A) were measured. The relationship between TB/A anol BAEP were analyzed. Results Compared with group A and group B, group C was significantly higher in the TB and TB/A ( P 〈 0.05 ). Abnormal BAEP findings were closely associated with the TB/A ratio ( P 〈 0.05). Conclusion The TB/A ratio may be a useful factor to evaluate the possible risk of bilirubin encephalopathy in full term newborns with hyperbilirubinemia.
机构地区 郑州市儿童医院
出处 《医药论坛杂志》 2006年第2期22-23,共2页 Journal of Medical Forum
关键词 高胆红素血症 脑干听觉诱发电位 胆红素神经毒性 Hyperbilirubinemia BAEP Bilirubin encephalopathy
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