摘要
目的：寻找一种有效、安全及低粘度的宫腔镜下手术灌流液。方法：应用５％葡萄糖液作为灌流液行各类宫腔内手术５００例。对其中２２例于术前、术终、术后１小时、术后４小时、手术后次日晨抽血测定血钠、钾、氯、糖和血浆渗透压的变化。术中采用Ｂ超进行双项对比监视。结果：５００例手术后无１例出现经尿道电切前列腺（ＴＵＲＰ）综合征。血钾于术终、术后１小时、术后４小时逐渐下降（Ｐ＜０．０１），血钠、氯、血浆渗透压无明显变化（Ｐ＞０．０５），血糖于术后明显升高（Ｐ＜０．０１）；血钾变化可于手术次日晨恢复。血钾、钠、氯及血浆渗透压变化，与灌流液的吸收无相关性（Ｐ＞０．０５）；血糖变化，与灌流液的吸收有相关性（Ｐ＜０．０５）。血钠、钾最低点及血糖最高点，均出现在术后１小时。结论：５％葡萄糖液作为宫腔镜下手术的灌流液是安全的。
Objective:Toobservethechangesofplasmaelectrolytesandosmolarityduringandaftertranscervicalresectionofendometriumusing5%dextrosesolutionasdistendingmedium.Meth-ods:Weused5%dextrosesolutionasdistendingmediumfor500casesofoperativehysteroscopy.Plasmasodium,potasium,chloride,glucoseconcentrationsandplasmaosmolarityweremeasuredbefore,attheendof1hour,4hoursandthedayafteroperationrespectivelyin22cases.Results:Noneofthe500casespresentedwithtransurethralresectionofprostate(TURP)syndrome.Noap-parentchangewerefoundinplasmasodium,chlorideconcentrationsandplasmaosmolarity.Plasmapotasiumconcentrationdecreasedgradualybutsignificantly4hoursaftersurgery.Theelevationofplasmaglucoseconcentrationwassignificantandwaspositivelycorrelatedwiththeabsorptionof5%dextrose.Alchangesofplasmaelectrolytesandosmolarityrestoredinthenextmorning.Itwas1houraftersurgerythatthelowestplasmasodium,potassiumconcentrationaswelasthehighestplasmaglucoseconcentrationappeared.Therefore,itisimportanttoobservepatient1hourafterop-eration.Conclusions:5%dextrosesolution,usedasthedistendingmedium,issafeandinexpensive,andcouldbewidelyappliedintranscervicalresectionofendometrium.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1996年第5期302-304,共3页
Chinese Journal of Obstetrics and Gynecology
