摘要
目的探讨口服心得安试验对功能性ST-T改变的临床价值。方法分析86例40岁以上伴有心悸、胸闷、气短症状,静息心电图有ST段水平或下斜型压低,T波低平的患者,通过口服心得安药物20 mg,分别在30、60、90、120 min描记心电图观察其变化。结果口服心得安20 mg 60 min后描记心电图,86%女性S-T段恢复正常,呈阳性改变,与男性组相比有明显差异性(P<0.05);与男性不同年龄组相比,随年龄增加阳性率逐渐降低,无明显差异性(P>0.05)。结论 86%以上的女性ST-T改变是植物神经功能紊乱所致,为功能性改变,与器质性ST-T改变无相关性和必然联系,对冠心病诊断敏感性为92.3%,特异性为90.6%.阳性预测价值为88.9%。
Objective To study the clinical value of propranolol test in ST-T functional change. Methods 86 patients above 40 years old with palpitation, stuffy chest, hard breath, lower ST-T, and low and flat T wave were analyzed by taking 20 mg of propranolol orally and observing ECG changes at 30, 60, 90 and 120 min. Results ST-T of 86% females recovered to normal after taking 20 mg propranolol for 60 min, and there is a significant difference when compared with control(P 〈 0.05). ST-T recovery was gradually decreased in male as age increased. Conclusion More than 86% females' ST-T changes were caused by functional disorders of autonomic nerves, and had no correlation with ST-T organic changes. Its diagnostic sensitivity to coronary heart disease was 92.3%, its specificity was 90.6% and positive evaluation value was 88.9%.
出处
《兰州大学学报(医学版)》
CAS
2006年第1期21-22,29,共3页
Journal of Lanzhou University(Medical Sciences)