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乳腺癌病人手术前后几项免疫指标变化的临床意义 被引量:1

Clinical significance of changes of some immune indexes in the patients with breast cancer before and after operation
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摘要 本研究采用免疫学方法对70例乳腺癌、24例乳腺良性疾病、30例健康成人进行NK活性、IL-2、LTT、IgG、IgA等项免疫指标的测定。结果表明:乳腺癌患者手术前NK活性、IL一2、LTT明显低于正常对照组及良性疾病组。术后1周,3项指标进一步降低,术后第4周恢复至正常水平,术后复发者,3项指标又降低。IgG、IgA术前明显高于正常人,术后第4周降至正常水平,术后复发者,二者又升高。提示:机体免疫功能的变化与乳腺癌的发生、发展有密切相关性。 The levels of NK vitality,IL-2.LTT,IgG,IgA were measured by immune method in70 patients with breast cancer and 24 patients with henign breast disease and 30 healthy individuals,The result showed that the levels of NK vitality, IL-2 and LTT in Datients with breast cancer weresignificantly lower than those in control group and benign breast disease group before operation,andthey disthcttly decreased in the first week after operation and increased to the normal in the fourthweek after operation,The three indexes decreased again in the patients with breast cancer recurrence.The levels of IgG and IgA in the patients with breast cancer were significantly higher than those incontrol group before operation,and they decreased to the normal in the fourth week after operationand increased again if the breast recurrence happened.These results suggested that there was close re-lationship between body immune function and the development of breast cancer.
出处 《白求恩医科大学学报》 CSCD 1996年第4期368-371,共4页 Journal of Norman Bethune University of Medical Science
基金 吉林省卫生厅资助
关键词 NK细胞 免疫性 乳腺癌 外科手术 NK vitality IL-2 LTT breast cancer IgG IgA
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