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复方甘草酸苷治疗抗结核药药物性肝炎的临床观察 被引量:3

The clinical observation of monoammonium glycyrrihizinate on hepatitis resulted from antituberclous drugs
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摘要 目的观察复方甘草酸苷治疗抗结核药药物性肝炎的临床疗效。方法将48例抗结核药引起的药物性肝炎患者随机分成治疗组27例和对照组21例。治疗组给予复方甘草酸苷治疗4周,对照组给予能量合剂治疗4周,观察治疗前后临床症状和血生化指标的变化。结果治疗组患者的临床症状和肝功能改善情况显著优于对照组(P<0.05)。结论复方甘草酸苷有很好的保肝、降酶作用,未见不良反应。 Objective To observe the clinical effects of Stronger Meo-Minophagen C (monoammonium glycyrrihizinate ) in the treatment on hepatitis resulted from antituberculous drugs. Methods 48 cases of hepatitis resulted from autituberculous drugs were randomly divided into the treatment group and the control group. The blood biochemical parameters were determined before and after treatment. Results There were differences in recovery rate in the two groups. The chinical manifestations, scram TBIL and ALT improved. Conlusion monoammonium glycyrrihizinate is effective for liver function damage caused by antituberculosis for its protective, anti-inflammatatoty function, monoammonium glycyrrihizinate is also a safe medicine with less side effects and therefore is recmmendable for treatment of liver injury caused by antitubercalosis.
作者 左起禧
出处 《实用肝脏病杂志》 CAS 2006年第2期87-87,83,共2页 Journal of Practical Hepatology
关键词 药物性肝炎 抗结核药 复方甘草酸苷 治疗 Tronger Neo-Minophagen Antituberculosis Hepatitis
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  • 1陈国桢.内科学[M].人民卫生出版社,1986.23.
  • 2宋士德.实用医药管理学[M].武汉:武汉测绘科技大学出版社,1994.193.
  • 3日野 邦彦 等.慢性肝炎和复方甘草甜素注射液疗法[J].(日文资料)医学和药学,1994,31(2):2-2.

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