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原发性肝癌患者介入治疗前后血清E-cad和SIL-2R检测的临床意义

Clinical Values of E-cad and SIL-2R Levels in Patients with Primary Liver Cancer before and after Interventional Therapy
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摘要 目的分析32例原发性肝癌患者介入治疗前后血清上皮钙粘蛋白(E-cad)和SIL-2R含量的变化及临床意义。方法采用酶联法测定血清上皮钙粘蛋白和SIL-2R含量,并与35例正常对照作对比。结果原发性肝癌患者介入治疗前血清上皮钙粘蛋白和SIL-2R水平显著高于对照组(P<0.01),介入治疗后6个月复发者血清上皮钙粘蛋白和SIL-2R水平持续异常,未复发者血清上皮钙粘蛋白和SIL-2R水平恢复正常。结论E-cad和SIL-2R的变化与原发性肝病病情和预后密切相关。 Objective To analyze the levels of E-cad and SIL-2R in 32 patients with primary liver cancer before and after interventions[ therapy. Method Serum E-cad and SIL-2R were detected hy ELTSA in 32 patients with primary liver cancer and compared with those in 35 normal controls. Results Before interventional therapy serum E-cad and SIL-2R levels were higher than those in normsl controls (P〈0.01). The levels of E-cad and SIL-2R were continualy abnormal in recurrent potients after interventionsl therapy for six months. The levels of E-cad and SIL-2R were normal in patients without recurnent after interventional therapy. Conclusion The variety of E-cad and SIL-2R associated with disease condition and prognosis of the primary liver cancer.
出处 《临床输血与检验》 CAS 2006年第2期114-115,共2页 Journal of Clinical Transfusion and Laboratory Medicine
关键词 原发性肝癌 上皮钙粘蛋白 可溶性白细胞介素-2受体 Primary liver cancer Cadherin cad Soluble interleukin-2 receptor
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  • 1黄华艺,查锡良.连环蛋白与肿瘤[J].中华病理学杂志,2000,29(3):227-229. 被引量:45
  • 2梁业民,吕惠兰,田萍,杨欣,梁超前.鼻咽癌患者放疗前后外周血sIL—2R水平测定[J].四川肿瘤防治,1996,9(4):20-21. 被引量:17
  • 3Gofuku J,Shiozaki H,Doki Y,et al.Characterization of soluble E-cadherin as a disease marker in gastric cancer patients[J].Br J cancer,1998,78(8):1095-1101.
  • 4Gioffi M,Gazzerro P,Finizio BD,et al.Serum-soluble E-cadherin fragments in lung cancer[J].Tumori,1999,85(1):32-34.
  • 5Ahmed MI,Abd-Elmotelib F,Farag RM,et al.Evaluation of some tissue and serum biomarkers in prostatic carcinoma among Egyptian male [J].Clin Biochem,1999,32(6):439-445.
  • 6Bosch Fx,Ardl C,Abel U,et al.E-cadberin is a selective and strongly dominant prognostic factor in squamous cell carcinoma:a comparison of E-cadherin with desmosomal components [J].Int J Cancer,2005,114(5):779-790.
  • 7Durkan GC,Brotherick I,Mellon JK.The impact of transurethral resection of bladder tumour on serum levels of soluble E-cadherin[J].BJU Int,1999,83 (4):424-428.
  • 8张允平,蔡振范.Graves病患者血清可溶性白介素2受体水平及临床意义[J].标记免疫分析与临床,1996,3(3):172-173. 被引量:35
  • 9高任卿 李金平 赵相平.病毒性肝炎白介素—2受体水平的动态关察[J].中华医学检验杂志,1996,14(4):48-48.
  • 10Rubin LA,Kurman CC,Fritz ME,et al.Soluble interleukin-2 receptor and releaned from activated human lymphoid cells in vitro[J].J Immunol,1985,135(11)3172-3177.

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