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未成熟树突状细胞诱导皮肤移植免疫耐受的研究进展 被引量：1

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摘要 树突状细胞（dendritic cell，DC）是一类重要的专职抗原呈递细胞，虽然在体内的数量较少，但是其强大的抗原呈递和处理功能在机体的免疫反应中起重要的作用。DC的发育分化过程伴随着其由未成熟的前体细胞向成熟细胞的转变，未成熟的DC（immature dendritic cell，imDC）与成熟DC（mature dendritic cell，mDC）在表型特征以及生物学功能上都有区别，而imDC最大的特点就是在体外可以诱导T淋巴细胞特异性低应答。临床上同种异体皮肤移植是目前大面积深度烧伤患者早期创面覆盖最直接、
作者 王永权 彭毅志
机构地区 第三军医大学西南医院全军烧伤研究所创伤
出处 《中华烧伤杂志》 CAS CSCD 北大核心 2006年第2期147-150,共4页 Chinese Journal of Burns
关键词 同种异体皮肤移植 树突状细胞 未成熟 移植免疫耐受 细胞诱导 抗原呈递细胞 cell 生物学功能 细胞特异性 免疫反应
分类号 R392.4 [医药卫生—免疫学]
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参考文献23

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二级参考文献25

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中华烧伤杂志
2006年 第2期

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