摘要
目的:了解胸段食管鳞癌腹腔淋巴结转移特点及对预后的影响,探讨合理的腹腔淋巴结清除范围。方法:对241例手术切除胸段食管鳞癌患者的临床资料进行回顾性分析。结果:腹腔淋巴结转移率32·4%,转移度9·8%。肝总动脉旁、腹腔动脉旁及肝十二指肠韧带内淋巴结转移度分别为6·6%、6·9%和6·3%。影响腹腔淋巴结转移的因素为肿瘤部位、浸润深度及组织分化程度。患者术后3年腹腔局部复发率为5·4%。有腹腔淋巴结转移患者的术后3年生存率为42·3%,低于无淋巴结转移患者的70·6%,P<0·01。结论:腹腔淋巴结转移是影响食管癌切除患者预后的一个主要因素,对腹腔淋巴结的广泛清除可以降低术后的局部复发率。
OBJECTIVE： To study the characteristics of abdominal lymph node metastases of squamous-cell carcinoma of thoracic esophagus and its influence on patients prognosis and to find reasonable dissecting range of abdominal lymph node. METHODS： The clinical date of 241 patients who had undergone resection of thoracic esophageal carcinoma were analysed retrospectively. RESULTS： Abdominal lymph node metastases were found in 78 of the 241 treated patients （32.4%）. In 3 181 abdominal lymph nodes dissected, metastases existed in 312 （9.8%）. Lymph node metastatic rates of common hepatic artery, celiac trunk and hepatoduodenal ligament were 6.6%, 6.9% and 6.3% respectively. Tumor site, tumor differentiation and the depth of tumor invasion were factors influencing abdominal lymph node metastases. The abdominal local recuring rate was 5.4 % in the postoperative. The 3-year survival rate of the patients with lymph node metastasis was 42.3 %, being much lower than that of patients with no lymph node metastasis （51.9%）, P〈 0. 01. CONCLUSION： Abdominal lymph node metastasis is one of key factors affecting the prognosis of patients, it could decrease postoperative local recuring rate by extensive dissecting abdominal lymph node.
出处
《中华肿瘤防治杂志》
CAS
2006年第5期365-367,共3页
Chinese Journal of Cancer Prevention and Treatment
关键词
食管肿瘤
腹腔
淋巴转移
淋巴结切除术
预后
esophageal neoplasm
abdomen
lymphatic metastasis
lymphadenectomy
prognosis
