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核酸适体技术研究进展 被引量:20

Current Reviews in Aptamers
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摘要 核酸适体(aptam er)指的是经体外筛选技术SELEX(指数富集配体系统进化)筛选出的能特异结合蛋白质或其他小分子物质的寡聚核苷酸片段,对可结合的配体有严格的识别能力和高度的亲和力。核酸适体在生物传感器、新药开发以及纳米技术等方面有着广泛的用途,本文对核酸适体近两年的研究进展进行综述。 Aptamers are oligo-nucleotides which exponential enrichment) in vitro, it can bind protein Researches on aptamers have achieved much progress article has reviewed the researches and applications of are selected by SELEX (systematic evolution of ligands by or other small molecules with high specificity and affinity. in biosensor, drug development and nano technology. This aptamers in the past two years.
出处 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2006年第2期463-466,共4页 Journal of Biomedical Engineering
关键词 核酸适体 指数富集配体系统进化 生物传感器 新药开发 纳米技术 Aptamer Systematic evolution of ligands by exponential enrichment(SELEX) Biosensor Drug development Nano technology
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参考文献23

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二级参考文献28

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