摘要
目的探讨肝硬化失代偿期的临床特点和死亡原因,有助于提高肝硬化的预防及治疗水平。方法回顾性分析该院消化内科1999年5月至2005年9月期间确诊肝硬化失代偿期患者死亡病例的临床资料。结果肝硬化失代偿期患者死亡前腹水、门静脉高压、低蛋白血症、上消化道出血、肝性脑病、肝癌、肝肾综合征出现率分别为95.2%(40/42)、97.6%(41/42)、95.2%(40/42)、88.1%(37/42)、54.8%(23/42)、26.2%(11/42)、21.4%(9/42);低钠低氯血症、低钙、低钾发生率分别为40.5%(17/42)、47.6%(20/42)、38.1%(16/42);脾功能亢进占71.4%(30/42),胆囊壁水肿、毛糙占59.5%(25/42),胆囊结石占35.7%(15/42);EKG以Q-T间期延长多见。主要死亡原因为失血性休克、肝性脑病、多器官功能衰竭。结论肝硬化失代偿期并发症多,平均病程3年左右。预防和处理好肝硬化并发症,尤其是上消化道出血、肝性脑病是降低肝硬化病死率的关键。
Aim To analyze the clinical characteristics and death causes of patient with decompensated hepatocirrhosis in order to improve its prevention and treatment. Methods The clinical materials about death patients with decompensated hepatocirrhosis during May 1999 to September 2005 in our hospital were analyzed retrocpectively. Results Before death, the displayed rates of ascites, portal hypertension,hypoalbumenmia, upper gastrointestinal hemorrhage, hepatic encephalopathy, primary carcinoma of the liver, hepatorenal syndrome were 95.2% （40/42） ,97.6% （41/42） ,95.2% （40/42） ,88.1% （37/42）, 54.8% （23/42）, 26.2% （11/42） ,21.4% （9/42） respectively. The displayed rates of hyponatremia and hypochlorinemia, hypocalciumia, hypokalemia were 40.5% （ 17/42 ） ,47, 6% （20/ 42）, 38.1% （16/42） respectively, Hypersplenism was 71,4% （30/42） , the wall of cholecyst dropsy and roughness 59.5 % （25/42）, cholelithiasis 35.7% （15/42）. Q-T interphase delay was familiar with electrocardiogram. Loss blood shock, gastrointestinal hemorrhage, hepatic encephalopathy and multiple organ failure are major causes of death. Conclusion There were many complications in patients with liver cirrhosis. The average ill-course was about 3 years. Prevention of complications, especially upper gastrointestinal hemorrhage and hepatic encephalopathy are the keys to reduce mortality of the paitents with liver cirrhosis.
出处
《安徽医药》
CAS
2006年第4期285-286,共2页
Anhui Medical and Pharmaceutical Journal
关键词
肝硬化
失代偿
死亡
并发症
hepatocirrhosis
decompensated
death
complications
