摘要
目的:总结平阳霉素(PYM)病变内注射治疗小儿颌面部静脉-微静脉畸形的疗效。方法:1997年1月～2005年6月,收治颌面部静脉-微静脉畸形患儿306例(385个病变),男123例,女183例,男女比为1∶1.49;年龄1个月～12岁,其中6个月以内172例,占56.21%。采用PYM病变内注射治疗,7～10d注射1次,3～5次为一个疗程。结果:经0.5～8.5a随访,治愈156例(50.98%),基本治愈116例(37.91%),好转34例(11.11%)。治愈和基本治愈272例,占88.89%,有效率为100%。结论:PYM治疗小儿颌面部静脉-微静脉畸形疗效高,疗程较短,是一种简便、安全的有效方法。
PURPOSE： To evaluate the effect of intralesional injection of Pingyangmycin（PYM） for treatment of venousvenular malformation in the maxillofacial regions of children. METHODS： The medical records of 306 patients with venous-venular malformation in the maxillofacial regions between January 1997 and June 2005 were reviewed. One hundred and twenty-three of the patients were men, and one hundred and eighty-three were woman, the sex ratio was 1： 1.49. The patients aged from one month to 12 years, 172 were less than 6 months （56.21%）. Pingyangmycin was injected into the center or in the vicinity of the venous-venular malformations, and repeated every 7 to 10 days. This cycle were repeated 3 to 5 times when necessary. RESULTS： Three hundred and six patients were followed up for 6 to 102 months. Complete response was obtained in 156 cases （50.98%）, partial response in 116 cases （37.91%）, and improvement in 34 cases （11.11%）. The overall response rate was 100%, and the curative rate was 88.89%. CONCLUSION： This method is safe, simple and effective for venous-venular malformation in the maxillofacial regions of children.
出处
《上海口腔医学》
CAS
CSCD
2006年第2期136-139,共4页
Shanghai Journal of Stomatology
关键词
平阳霉素
儿童
颌面部
静脉-微静脉畸形
病变内注射
Pingyangmycin
Children
Maxillofacial region
Venous-venular malformation
Intralesional injection
