摘要
目的:探讨共轭亚油酸(CLA)强化乳对小鼠体脂及血脂的影响。方法:选4w龄的雄性昆明种小鼠40只,随机分成四组,每组10只,分别在牛奶中添加0%、0.1%、0.5%、1.0%的CLA喂养小鼠4w后,测定体重、腹脂重、体脂含量、饲料利用率及血浆甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇含量(HDL)与脂蛋白脂酶(LPL)活性。结果:小鼠的体增重、腹脂重、体脂含量及饲料利用率都随着乳中CLA的添加量增加而降低,与对照组比,当添加0.5%时达到显著差异;在乳中添加CLA可以降低小鼠血浆中的TG与TC含量,提高HDL含量和LPL活性,降低动脉硬化指数(TC-HDL/HDL)。TC含量在添加0.5%CLA时最低,其它的血脂指标在添加1.0%CLA时效果最好。结论:共轭亚油酸强化乳有降低体脂和血脂的作用。
Objective： To study the effects of fortified conjugated linoleic acid （CLA） milk on body fat and plasma lipids in mice. Method： Forty male Kunming mice of 4 w old were randomly divided into four groups and fed diet and milk supplemented with 0%, 0.1%, 0.5%, 1.0% CLA （percent of diet, dry mass） respectively for 4 w. Weight gain, body fat, intra-abdominal fat, feed conversion efficiency and plasma TG, TC, HDL, LPL were measured. Results： At the end of the experiment, all these physiological indices were decreased with increasing CLA in the milk and were lower significantly than that of control group when supplemented with 0.5% CLA in milk. TG, TC and （TC-HDL）/HDL were decreased, but HDL and LPL were increased with increasing CLA amount in the milk. TG, HDL, LPL and （TC-HDL）/HDL were best when fed the milk supplemented with 1.0% CLA, while TC was the lowest when fed the milk supplemented with 0.5% CLA. Conclusion： The fortified conjugated linoleic acid is effective in lowering body fat and blood lipids.
出处
《营养学报》
CAS
CSCD
北大核心
2006年第2期120-123,共4页
Acta Nutrimenta Sinica
基金
安徽省教育厅自然科学基金(No.2004KJ139zd)
关键词
共轭亚油酸
强化乳
体脂
血脂
conjugated linoleic acid （CLA）
fortified milk
body fat
plasma lipids
