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母性效应基因的研究进展 被引量:2

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摘要 个体发育中存在一个关键过程即由母性基因组活动向胚胎基因组活化的转变。这需要依赖贮存在卵母细胞中的母性mRNA和蛋白质。早在对果蝇的研究中已经证实,母性效应基因(mater-nal-effect gene)对卵母细胞向胚胎转变以及胚胎的早期发育起着关键作用。近年,越来越多的证据表明母性效应基因在哺乳动物发育中同样起着关键作用,并证明了人类相似母性效应基因的存在。本文综合了各方面对哺乳动物母性效应基因的研究结果,简述了其研究现状及新近的进展。
出处 《生理科学进展》 CAS CSCD 北大核心 2006年第2期153-155,共3页 Progress in Physiological Sciences
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